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497-25-6 - 2-Oxazolidinone, 99% - 2-Oxazolidone - A14543 - Alfa Aesar

A14543 2-Oxazolidinone, 99%

Número CAS
497-25-6
Nombre Alternativo
2-Oxazolidone

Tamaño Precio ($) Cantidad Disponibilidad
25g 38,70
100g 107,00
500g 364,00
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2-Oxazolidinone, 99%

MDL
MFCD00005268
EINECS
207-840-9

Propiedades químicas

Fórmula
C3H5NO2
Peso molecular
87.08
Punto de fusión
84-89°
Punto de ebullición
220°/48mm
Solubilidad
Soluble in water.

Aplicaciones

2-Oxazolidinone is used as antimicrobials, in organisms it act as a protein synthesis inhibitors, targeting an early step involving the binding of N-formylmethionyl-tRNA to the ribosome. They are used for chiral synthesis. It has been used as an ethanolamine equivalent, also behaves as an aziridine equivalent as in the conversion of thiophenols or amines to their aminoethyl derivatives.

Notas

Store in cool, dry conditions in a well sealed container. Store away from oxidizing agents.

Referencias documentales

Hideaki Kakeya; Masayuki Morishita; Hiroyuki Koshino; Tetsu-ichiro Morita; Kimiko Kobayashi and Hiroyuki Osada. Cytoxazone:? A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces sp. J. Org. Chem. 1999, 64 (3), 1052-1053.

Guo-Jie Ho; David J. Mathre. Lithium-Initiated Imide Formation. A Simple Method for N-Acylation of 2-Oxazolidinones and Bornane-2,10-Sultam. J. Org. Chem. 1995, 60 (7), 2271-2273.

Has been used as an ethanolamine equivalent, e.g. in reaction with succinic anhydride to give 1-(2-hydroxyethyl)succinimide: Tetrahedron, 44, 261 (1988). Also behaves as an aziridine equivalent as in the conversion of thiophenols or amines to their aminoethyl derivatives: J. Org. Chem., 57, 6257 (1992).

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Beilstein
106251
Código de tarifa arancelaria unificado
2934.99
TSCA
Yes
RTECS
RQ2450000

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