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79-43-6 - Dichloroacetic acid, 99% - A14740 - Alfa Aesar

A14740 Dichloroacetic acid, 99%

Número CAS
79-43-6
Nombre Alternativo

Tamaño Precio ($) Cantidad Disponibilidad
100g 19,80
500g 38,97
2500g 121,54
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Dichloroacetic acid, 99%

MDL
MFCD00004223
EINECS
201-207-0

Propiedades químicas

Fórmula
Cl2CHCO2H
Peso molecular
128.94
Punto de fusión
9-11°
Punto de ebullición
192-194°
Punto de inflamabilidad
>110°(230°F)
Densidad
1.564
Índice de refracción
1.4620
Sensibilidad
Hygroscopic
Solubilidad
Miscible with water, ethanol, diethyl ether, n-octanol and acetone.

Aplicaciones

Dichloroacetic acid salts are used as drugs due to its inhibition of the enzyme pyruvate dehydrogenase kinase. It is also employed to stem the production of lactic acid to treat lactic acidosis. It is clinically essential in children to treat lactic acidosis.

Notas

Incompatible with strong oxidizing agents, strong bases and strong reducing agents.

Referencias documentales

Moderately strong acid which has been recommended for the catalysis of mixed acetal formation by reaction of alcohols with Ethyl­ vinyl­ ether, A15691 . Has also been used as an acid catalyst and deprotecting agent in various other applications including peptide synthesis.

Ding, Y.; Zhu, J.; Ji, D.; Cao, Y.; Ling, X.; Chen, W. Enhancing adsorption efficiency of dichloroacetic acid onto mesoporous carbons: Procedure optimization, mechanism and characterization. J. Colloid Interface Sci. 2015, 452, 134-140.

Scialdone, O.; Galia, A.; Sabatino, S.; Mira, D.; Amatore, C. Electrochemical Conversion of Dichloroacetic Acid to Chloroacetic Acid in a Microfluidic Stack and in a Series of Microfluidic Reactors. Chem. Electro. Chem. 2015, 2 (5), 684-690.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H314-H400

Causes severe skin burns and eye damage. Very toxic to aquatic life.

Indicaciones de precaución: P260-P273-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,3050
Beilstein
1098596
Clase de peligro
8
Grupo de embalaje
II
Código de tarifa arancelaria unificado
2915.40
TSCA
Yes
RTECS
AG6125000

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