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554-84-7 - 3-Nitrophenol, 98+% - A15312 - Alfa Aesar

A15312 3-Nitrophenol, 98+%

Número CAS
554-84-7
Nombre Alternativo

Tamaño Precio ($) Cantidad Disponibilidad
10g 54,38
50g 135,90
250g 559,80
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3-Nitrophenol, 98+%

MDL
MFCD00007240
EINECS
209-073-5

Propiedades químicas

Fórmula
C6H5NO3
Peso molecular
139.11
Punto de fusión
93-98°
Punto de ebullición
194°/70mm
Punto de inflamabilidad
>100°(212°F)
Densidad
1.490
Solubilidad
Soluble in water (30 mg/ml), ether, alcohol, acetone, and ethanol (700 mg/ml).

Aplicaciones

3-Nitrophenol is used as indicator in 0.3% Soln in 50% alcohol ph: 6.8 Colorless, 8.6 Yellow. It is used in the synthesis of RAGE inhibitors via the etherification of phenols. Also used in the synthesis of kinase inhibitors against epidermal growth factor receptor T790M mutation.

Notas

Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.

Referencias documentales

A. Alif; P. Boule; J. Lemaire. Photochemistry and environment XII: Phototransformation of 3-nitrophenol in aqueous solution.Journal of Photochemistry and Photobiology A.1990, 50 331-342.

Mohammad R.Haghighi Podeh; Sanjoy K. Bhattacharya; Mingbo Qu. Effects of nitrophenols on acetate utilizing methanogenic systems.Water Research.1995, 29 391-399.

Acid-base indicator: approx pH 6.6 - 8.6.

Has been used for the formation of active esters. These are more stable than the corresponding 4-nitrophenyl esters, but are sufficiently reactive for use in peptide synthesis: Synthesis, 465 (1979).

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H318-H315-H373-H302-H312-H335

Causes serious eye damage. Causes skin irritation. May cause damage to organs through prolonged or repeated exposure. Harmful if swallowed. Harmful in contact with skin. May cause respiratory irritation.

Indicaciones de precaución: P260-P261-P280-P305+P351+P338-P304+P340-P310-P362-P301+P312-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,6619
Beilstein
1907946
Clase de peligro
6.1
Grupo de embalaje
III
Código de tarifa arancelaria unificado
2908.99
TSCA
Yes
RTECS
SM1925000

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