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A15751 Homopiperazine, 98%

Número CAS
505-66-8
Nombre Alternativo
1,4-Diazacycloheptane
Hexahydro-1,4-diazepine

Stock No. Tamaño Precio ($) Cantidad Disponibilidad
A15751-14 25g 91,60
A15751-22 100g 259,00
A15751-36 500g 590,00
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Homopiperazine, 98%

MDL
MFCD00006933
EINECS
208-016-1

Propiedades químicas

Fórmula
C5H12N2
Peso molecular
100.17
Punto de fusión
38-44°
Punto de ebullición
168-170°
Punto de inflamabilidad
64°(147°F)
Densidad
0.95
Storage & Sensitivity
Hygroscopic. Air Sensitive. Ambient temperatures.
Solubilidad
Soluble in water.

Aplicaciones

Homopiperazine is used to prepare 1,4-bis-(2-thiazolyl)-1,4-diazacycloheptane by reacting with 2-bromo-thiazole. It acts as an intermediate for repaglinide and fasudil hydrochloride. It is also used in the preparation of potent H3 receptor antagonists, which is used for the treatment of neurodegenerative conditions. Further, it is used in vesicant, cosmetic, emulsifier and energetic material. It acts as a corrosion inhibitor for iron. In pharmaceuticals, it is employed as antipyretic and reducing blood sugar, adiposity, calm, antipsychotic and anti-nervous.

Notas

Hygroscopic. Air sensitive. Incompatible with strong oxidizing agents and strong acids.

Referencias documentales

Keypour, H.; Rezaeivala, M.; Mirzaei-Monsef, M.; Sayin, K.; Dilek, N.; Unver, H. Synthesis and characterization of Co(II), Ni(II), Cu(II) and Zn(II) complexes with a new homopiperazine macrocyclic Schiff base ligand. Inorg. Chim. Acta 2015, 432, 243-249.

Vinodh, R.; Bhagiyalakshmi, M.; Hemalatha, P.; Ganesh, M.; Peng, M. M.; Palanichamy, M.; Cha, W. S.; Jang, H. T. Homopiperazine Grafted Mesoporous Silicas from Rice Husk Ash for CO2 Adsorption. J. Nanosci. Nanotechnol. 2014, 14 (6), 4639-4648.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H312-H314

Harmful in contact with skin. Causes severe skin burns and eye damage.

Indicaciones de precaución: P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Otras referencias

Beilstein
102711
Clase de peligro
8
Grupo de embalaje
III
Código de tarifa arancelaria unificado
2933.99
TSCA
Yes
RTECS
HM3850000

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