Cookies disclaimer

Estoy de acuerdo utilizamos cookies para mejorar la experiencia de navegación del usuario y para estudiar cómo se utiliza nuestro sitio web. si navega por nuestro sitio web, estará aceptando el uso de las cookies en las condiciones establecidas en la presente política de cookies. esta política puede ser actualizada, por lo que le invitamos a revisarla de forma regular

431-47-0 - Methyl trifluoroacetate, 98+% - Trifluoroacetic acid methyl ester - A17338 - Alfa Aesar

A17338 Methyl trifluoroacetate, 98+%

Número CAS
431-47-0
Nombre Alternativo
Trifluoroacetic acid methyl ester

Tamaño Precio ($) Cantidad Disponibilidad
50g 53,90
250g 238,00
1000g 829,00
Añadir al carrito Añadir al presupuesto al por mayor Ver artículo

Methyl trifluoroacetate, 98+%

MDL
MFCD00000417
EINECS
207-074-5

Propiedades químicas

Fórmula
CF3CO2CH3
Peso molecular
128.05
Punto de fusión
-78°
Punto de ebullición
43-44°
Punto de inflamabilidad
-18°(-0.4°F)
Densidad
1.283
Índice de refracción
1.2900
Sensibilidad
Moisture Sensitive
Solubilidad
Not miscible or difficult to mix in water.

Aplicaciones

Useful reagent for trifluoroacetylation of amines under mild conditions. In the presence of 1,1,3,3-Tetramethyl­guanidine, has also been used for the N-acylation of amino acids. It is used as an intermediate in the synthesis of pharmaceutical and agricultural chemicals. The chemical reactions usually involve nucleophilic substitution of the ester and are useful for the preparation of trifluoroacylated compounds.

Notas

Moisture sensitive. Store away from strong bases, water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect from humidity.

Referencias documentales

Langlois BR and Roques N. Nucleophilic trifluoromethylation of aryl halides with methyl trifluoroacetate.J. Fluor. Chem.,2007,128(10), 1318-1325.

M. N. Vargaftik, et al. Highly selective partial oxidation of methane to methyl trifluoroacetate.J. Chem. Soc., Chem. Commun.,1990,15, 1049-1050.

Useful reagent for trifluoroacetylation of amines under mild conditions. In the presence of 1,1,3,3-Tetramethyl­guanidine, A12314, has also been used for the N-acylation of amino acids: Synthesis, 399 (1976).

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H225-H314-H318

Highly flammable liquid and vapour. Causes severe skin burns and eye damage. Causes serious eye damage.

Indicaciones de precaución: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Beilstein
1756070
Clase de peligro
3
Grupo de embalaje
II
Código de tarifa arancelaria unificado
2915.90
TSCA
Yes

Recomendado

Visto recientemente

Productos químicos

Ciencias de la vida

Metales & materiales

Catalizadores

Análisis y material de laboratorio