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68-41-7 - D-Cycloserine, 98+% - (R)-(+)-4-Amino-3-isoxazolidinone - A18000 - Alfa Aesar

A18000 D-Cycloserine, 98+%

Número CAS
68-41-7
Nombre Alternativo
(R)-(+)-4-Amino-3-isoxazolidinone

Tamaño Precio ($) Cantidad Disponibilidad
1g 51,20
5g 197,00
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D-Cycloserine, 98+%

MDL
MFCD00005353
EINECS
200-688-4

Propiedades químicas

Fórmula
C3H6N2O2
Peso molecular
102.09
Punto de fusión
137° dec.
Sensibilidad
Air Sensitive
Solubilidad
Soluble in water. Slightly soluble in methanol and propylene glycol. Insoluble in chloroform and ether.

Aplicaciones

Cycloserine is an amino acid analog antibiotic used for the treatment of tuberculosis and rarely used for the treatment of noninfectious diseases. It acts as a competitive inhibitor of D-alanine during peptidoglycan synthesis. It inhibits bacterial cell wall biosynthesis and prevents the conversion of D-Alanine to L-Alanine.

Notas

Air Sensitive. Store in cool place. Incompatible with strong oxidizing agents.

Referencias documentales

Philbert, J.; Beeske, S.; Belzung, C.; Griebel, G. The CRF1 receptor antagonist SSR125543 prevents stress-induced long-lasting sleep disturbances in a mouse model of PTSD: Comparison with paroxetine and d-cycloserine. Behav Brain Res 2015, 279, 41-46.

Hofmann, S. G.; Carpenter, J. K.; Otto, M. W.; Rosenfield, D.; Smits, J. A. J.; Pollack, M. H. Dose timing of d-cycloserine to augment cognitive behavioral therapy for social anxiety: Study design and rationale. Contemp. Clin. Trials 2015, 43, 223-230.

Indicaciones de peligro y de precaución del GHS

Indicaciones de precaución: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,2751
Beilstein
80798
Código de tarifa arancelaria unificado
2941.90
TSCA
No
RTECS
NY2975000

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