Cookies disclaimer

Estoy de acuerdo utilizamos cookies para mejorar la experiencia de navegación del usuario y para estudiar cómo se utiliza nuestro sitio web. si navega por nuestro sitio web, estará aceptando el uso de las cookies en las condiciones establecidas en la presente política de cookies. esta política puede ser actualizada, por lo que le invitamos a revisarla de forma regular

220141-70-8 - 5-Fluoroorotic acid monohydrate, 98% - 5-Fluorouracil-6-carboxylic acid monohydrate - B21290 - Alfa Aesar

B21290 5-Fluoroorotic acid monohydrate, 98%

Número CAS
220141-70-8
Nombre Alternativo
5-Fluorouracil-6-carboxylic acid monohydrate

Tamaño Precio ($) Cantidad Disponibilidad
50mg 33,30
250mg 113,00
1g 280,00
Añadir al carrito Añadir al presupuesto al por mayor Ver artículo

5-Fluoroorotic acid monohydrate, 98%

MDL
MFCD00150658
EINECS
211-876-0

Propiedades químicas

Fórmula
C5H3FN2O4•H2O
Peso molecular
192.11 (174.09anhy)
Punto de fusión
ca 255° dec.
Solubilidad
Soluble in water, dimethyl sulfoxide, 50mg in 1ml (1:1 ammonium hydroxide: water) with gentle heating.

Aplicaciones

5-Fluoroorotic Acid, Monohydrate (5-FOA) has become a valuable tool for research in the field of molecular genetics and has been employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5í-phosphate decarboxylation.

Notas

Store in freezer (-20°C). Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Referencias documentales

W. M. Macintyre; and M. Zirakzadeh. The crystal and molecular structure of the monohydrate of the rubidium salt of 5-fluoroorotic acid. Acta Cryst., 1964, 171305-1311.

V. H. Bono Jr.; C. C. Cheng; E. Frei III; and M. G. Kelly. Methyl-5-fluoroorotate: Synthesis and Comparison with 5-Fluoroorotic Acid with Respect to Biological Activity and Cell Entry. Cancer Res., 1964, 24513.

Reagent used in the selection of mutant URA3 gene strains of Saccharomyces Cerevisiae: Genetics, 107, 179 (1984); Methods Enzymol., 154, 164 (1987).

Potential antimalarial agent: Antimicrob. Agents Chemother., 40, 914 (1996).

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,4176
Beilstein
181933
Código de tarifa arancelaria unificado
2933.59
TSCA
No
RTECS
UV7800000

Recomendado

Visto recientemente

Productos químicos

Ciencias de la vida

Metales & materiales

Catalizadores

Análisis y material de laboratorio