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329-98-6 - alpha-Toluenesulfonyl fluoride, 99% - Phenylmethanesulfonyl fluoride - Phenylmethylsulfonyl fluoride - B22146 - Alfa Aesar

B22146 alpha-Toluenesulfonyl fluoride, 99%

Número CAS
329-98-6
Nombre Alternativo
Phenylmethanesulfonyl fluoride
Phenylmethylsulfonyl fluoride

Tamaño Precio ($) Cantidad Disponibilidad
1g 21,20
5g 56,90
25g 216,00
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alpha-Toluenesulfonyl fluoride, 99%

MDL
MFCD00007424
EINECS
206-350-2

Propiedades químicas

Fórmula
C7H7FO2S
Peso molecular
174.19
Punto de fusión
92-94°
Sensibilidad
Moisture Sensitive
Solubilidad
Soluble in ether, benzene, anhydrous ethanol, methanol, 2- propane. Hydrolyses in water.

Aplicaciones

α-Toluenesulfonyl fluoride (PMSF) is used in the preparation of cell lysates to inhibit protein digestion. It is a widely used fatty acid amid hydrolase (FAAH) inhibitor for pretreatment of brain membrane preparations when testing CB1 receptor activity.

Notas

Moisture sensitive. Store away from strong oxidizing agents, amines, bases, water/ moisture. Store at 4°C

Referencias documentales

C Pinsky; A K Dua; F S LaBella. Phenylmethylsulfonyl fluoride (PMSF) given systemically produces naloxone-reversible analgesia and potentiates effects of beta-endorphin given centrally. Life Sciences. 1982, 31 (12-13), 1193-1196.

G T James.Inactivation of the protease inhibitor phenylmethylsulfonyl fluoride in buffers. Analytical Biochemistry. 1978, 86 (2), 574-579.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H301-H314-H318

Toxic if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage.

Indicaciones de precaución: P260-P280-P301+P310-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Beilstein
2088311
Clase de peligro
8
Grupo de embalaje
III
Código de tarifa arancelaria unificado
2904.10
TSCA
Yes
RTECS
XT8040000

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