Cookies disclaimer

Estoy de acuerdo utilizamos cookies para mejorar la experiencia de navegación del usuario y para estudiar cómo se utiliza nuestro sitio web. si navega por nuestro sitio web, estará aceptando el uso de las cookies en las condiciones establecidas en la presente política de cookies. esta política puede ser actualizada, por lo que le invitamos a revisarla de forma regular

103-74-2 - 2-(2-Hydroxyethyl)pyridine, 99% - 2-Pyridineethanol - 2-(2-Pyridyl)ethanol - B23579 - Alfa Aesar

B23579 2-(2-Hydroxyethyl)pyridine, 99%

Número CAS
103-74-2
Nombre Alternativo
2-Pyridineethanol
2-(2-Pyridyl)ethanol

Tamaño Precio ($) Cantidad Disponibilidad
100g 27,20
500g 85,20
Añadir al carrito Añadir al presupuesto al por mayor Ver artículo

2-(2-Hydroxyethyl)pyridine, 99%

MDL
MFCD00006364
EINECS
203-140-2

Propiedades químicas

Fórmula
C7H9NO
Peso molecular
123.16
Punto de fusión
-8°
Punto de ebullición
235-238°
Punto de inflamabilidad
117°(243°F)
Densidad
1.095
Índice de refracción
1.5370
Sensibilidad
Hygroscopic
Solubilidad
Soluble in Chloroform (Slightly), Methanol (Slightly).

Aplicaciones

2-(2-Hydroxyethyl)pyridine is a metabolite of the anti-vertigo drug Betahistine. It acts as a reagent for protection of the 5'-phosphate of nucleotides as 2-pyridylethyl (Pet) esters. It is used for carboxyl protection of amino acids. It is also used to cleave such groups as Boc and Fmoc, and also to hydrogenolysis. It was used to prepare mononuclear nickel(II) acetate.

Notas

Hygroscopic. Store under dry inert gas. Store away from moisture, strong bases and oxidizing agents. Protect from humidity and water.

Referencias documentales

Miha Trdin; Valter Bergant; Ivan Leban; Nina Lah. Two concomitant polymorphs of monomeric nickel acetate with 2-pyridineethanol. Acta Chimica Slovenica. 2012, 59, (3), 478-483.

Takashi Niwa; Hideki Yorimitsu; Koichiro Oshima. Palladium-Catalyzed 2-Pyridylmethyl Transfer from 2-(2-Pyridyl)ethanol Derivatives to Organic Halides by Chelation-Assisted Cleavage of Unstrained Cmath image[BOND]Cmath image Bonds. Angewandte Chemie (International Edition). 2007, 46, (15), 2643-2645.

Reagent for protection of the 5'-phosphate of nucleotides as 2-pyridylethyl (Pet) esters. The group can be introduced by DCC-coupling, is stable to mild base, but can be cleaved by methoxide in pyridine-methanol: Chem. Ber., 103, 1032 (1970).

Has also been used for carboxyl protection of amino acids. Pet esters are stable to both mildly acidic and basic conditions used to cleave such groups as Boc and Fmoc, and also to hydrogenolysis. Cleavage is by quaternization with methyl iodide in the presence of mild base: Tetrahedron Lett., 25, 3971 (1984); Angew. Chem. Int. Ed., 23, 716 (1984). See Appendix 6.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H315-H319-H335-H227

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.

Indicaciones de precaución: P210-P261-P280-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Beilstein
111205
Código de tarifa arancelaria unificado
2933.39
TSCA
Yes
RTECS
UT2970450

Recomendado

  • A10943

    2,4-Dichlorophenylhydrazine hydrochloride, 98%
  • A11136

    Dopamine hydrochloride, 99%
  • A11430

    p-Toluenesulfinic acid sodium salt, 97% (dry wt.), water <5%
  • A12333

    2-Nitrophenol, 98%
  • L13310

    Zinc powder, -100 mesh, 97+%

Visto recientemente

Productos químicos

Ciencias de la vida

Metales & materiales

Catalizadores

Análisis y material de laboratorio