1-Aza-18-crown-6 is used as building block for the synthesis of bis-crown ethers, lariat ethers and other monofunctionalized macrocycles. It is also used as pharmaceutical intermediate.
Kamaluddin Abdur-Rashid; Dmitry G.Gusev; Alan J.Lough; Robert H.Morris. Intermolecular proton-hydride bonding in ion pairs:? Synthesis and structural properties of [K(Q)][MH5(PiPr3)2] (M = Os, Ru; Q = 18-crown-6, 1-aza-18-crown-6, 1,10-diaza-18-crown-6). Organometallics. 2000, 19, (5),834-843
Huimin Luo; Sheng Dai; Peter V.Bonnesen. Solvent extraction of Sr2+ and Cs+ based on room-temperature ionic liquids containing monoaza-substituted crown ethers. Anal. Chem. 2004, 76, (10),2773-2779
Indicaciones de peligro (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Indicaciones de precaución: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.