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146998-31-4 - 4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester, 98+% - DABCYL-N-succinimidyl ester - 4-[(Dimethylamino)azo]benzene-4'-carboxylic acid N-succinimidyl ester - H54402 - Alfa Aesar

H54402 4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester, 98+%

Número CAS
146998-31-4
Nombre Alternativo
DABCYL-N-succinimidyl ester
4-[(Dimethylamino)azo]benzene-4'-carboxylic acid N-succinimidyl ester

Tamaño Precio ($) Cantidad Disponibilidad
25mg 41,70
100mg 134,00
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4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester, 98+%

MDL
MFCD00467415

Propiedades químicas

Fórmula
C19H18N4O4
Peso molecular
366.37
Sensibilidad
Moisture Sensitive
Solubilidad
Soluble in DMSO.

Aplicaciones

4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester is a useful reagent (similar to MANCYL-SE) for labeling proteins or peptides through their amino-groups by forming stable peptide bonds. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles for fluorescent studies of proteins. Its fluorescent properties (has a characteristic broad and intense visible absorption but has no fluorescence) make it an ideal long wavelength quencher and it has been utilized as an acceptor chromophore in FRET studies. It is also used for N-terminal modification of peptides in automated synthesis.

Notas

Moisture sensitive. Incompatible with oxidizing agents and heat.

Referencias documentales

Desmond J O'Shea; Tomas C O'Riordan; Paul J O'Sullivan; Dmitri B.Papkovsky. Homogeneous time-resolved fluorescence assays for the detection of activity and inhibition of phosphatase enzymes employing phosphorescently labeled peptide substrates. Analytica Chimica Acta. 2007, 583,(2), 349-356.

 

Tomas C O'Riordan; James Hynes; Dmitri Yashunski; Gelii V.Ponomarev; Dmitri B.Papkovsky. Homogeneous assays for cellular proteases employing the platinum(II)-coproporphyrin label and time-resolved phosphorescence. Analytical Biochemistry. 2005, 342,(1), 111-119.

Indicaciones de peligro y de precaución del GHS

Indicaciones de precaución: P260-P201-P280-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Código de tarifa arancelaria unificado
2927.00
TSCA
No

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