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5305-40-8 - 4,6-Dichloropyrimidine-5-carboxaldehyde, 97% - H54449 - Alfa Aesar

H54449 4,6-Dichloropyrimidine-5-carboxaldehyde, 97%

Número CAS
5305-40-8
Nombre Alternativo

Tamaño Precio ($) Cantidad Disponibilidad
1g 33,30
5g 125,00
25g 500,00
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4,6-Dichloropyrimidine-5-carboxaldehyde, 97%

MDL
MFCD02257701

Propiedades químicas

Fórmula
C5H2Cl2N2O
Peso molecular
175.99
Punto de fusión
66-71°

Aplicaciones

4,6-Dichloropyrimidine-5-carboxaldehyde is used as a substrate in the synthesis of N-terminal surrogate in amino acid and peptide analogues.

Notas

Incompatible with strong oxidizing agents and strong acids. Store in cool place.

Referencias documentales

Li, B.; Yue, Z.; Xiang, H.; Lv, L.; Song, S.; Miao, Z.; Yang, C. Catalyst-free synthesis of benzofuran-fused pyrido[4,3-d]pyrimidines from 2-(2-hydroxyaryl)acetonitrile and 4,6-dichloropyrimidine-5-carbaldehyde through domino condensation reactions. RCS Adv. 2015, 4 (1), 358-364.

Schenone, S.; Radi, M.; Musumeci, F.; Brullo, C.; Botta, M. Biologically Driven Synthesis of Pyrazolo[3,4-d]pyrimidines As Protein Kinase Inhibitors: An Old Scaffold As a New Tool for Medicinal Chemistry and Chemical Biology Studies. Chem. Rev. 2014, 114 (14), 7189-7238.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Código de tarifa arancelaria unificado
2933.59
TSCA
No

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