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19916-73-5 - O6-Benzylguanine, 98% - H60274 - Alfa Aesar

H60274 O6-Benzylguanine, 98%

Número CAS
19916-73-5
Nombre Alternativo

Tamaño Precio ($) Cantidad Disponibilidad
250mg 40,20
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O6-Benzylguanine, 98%

MDL
MFCD00269931

Propiedades químicas

Fórmula
C12H11N5O
Peso molecular
241.25
Solubilidad
Soluble in methanol (20 mg/ml), and aqueous alkali (Heated).

Aplicaciones

O6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Notas

Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from strong oxidizing agents.

Referencias documentales

ME Dolan.; RB Mitchell.; C Mummert.; RC Moschel. Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents. Cancer research. 199175 (20), 29-35.

ME Dolan.; AE Pegg. O6-benzylguanine and its role in chemotherapy. Clinical Cancer Research. 19973 (1), 837-839.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Código de tarifa arancelaria unificado
2933.99
TSCA
No

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