5-Methyl-4,6-dihydroxypyrimidine was synthesized from formamidine hydrochloride. N-Formimino-n-glutamate was synthesized from formamidine hydrochloride. Formamidine hydrochloride was used in the synthesis of imidazoleglycerol phosphate (IGP).
Shan Liu,; Qinghe Gao,; Xia Wu,; Jingjing Zhang,; Kerong Ding,; Anxin Wu. Formamidine hydrochloride as an amino surrogate: I2-catalyzed oxidative amidation of aryl methyl ketones leading to free (N-H) α-ketoamides. Org. Biomol. Chem. 2015, 13 issue , 2239-2242.
H. M. Novais,; S. Steenken. Reactions of oxidizing radicals with 4,6-dihydroxypyrimidines as model compounds for uracil, thymine, and cytosine. J. Phys. Chem. 1977, 91 (2), 426-433.