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286961-14-6 - N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, 95% - H66193 - Alfa Aesar

H66193 N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, 95%

Número CAS
286961-14-6
Nombre Alternativo

Tamaño Precio ($) Cantidad Disponibilidad
1g 54,90
5g 206,00
25g 823,00
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N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, 95%

MDL
MFCD03840345

Propiedades químicas

Fórmula
C16H30BNO5
Peso molecular
327.23
Solubilidad
Soluble in most organic solvents. Insoluble in water.

Aplicaciones

Reagent used for suzuki-Miyaura cross-coupling using palladium phosphine catalyst, palladium-catalyzed ligand-controlled regioselective Suzuki coupling, wrenchnolol derivative optimized for gene activation in cells. Also used in Preparation of several enzymatic inhibitors and receptor ligands, orally active anaplastic lymphoma kinase inhibitors and oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes.

Notas

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Referencias documentales

Tang, Q; Gianatassio, R. Synthesis of 1,5-disubstituted tetrazoles via Suzuki-Miyaura cross-coupling of 5-chloro-1-phenyltetrazole. Tetrahedron Lett.2010513473-3476.

Neil A Strotman; Harry R Chobanian; Jiafang He; Yan Guo; Peter G Dormer; Christina M Jones; Janelle E Steves. Catalyst-controlled regioselective Suzuki couplings at both positions of dihaloimidazoles, dihalooxazoles, and dihalothiazoles. Journal of Organic Chemistry.201075(5), 1733-1739.

Indicaciones de peligro y de precaución del GHS

Indicaciones de precaución: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Código de tarifa arancelaria unificado
2934.99
TSCA
No

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