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65-19-0 - Yohimbine hydrochloride, 98+% - 17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride - J60185 - Alfa Aesar

J60185 Yohimbine hydrochloride, 98+%

Número CAS
65-19-0
Nombre Alternativo
17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride

Tamaño Precio ($) Cantidad Disponibilidad
1g 44,40
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Yohimbine hydrochloride, 98+%

MDL
MFCD00012674
EINECS
200-600-4

Propiedades químicas

Fórmula
C21H26N2O3•HCl
Peso molecular
390.91
Formulario
Powder
Punto de fusión
288-290°
Sensibilidad
Light Sensitive
Solubilidad
Soluble in dimethyl sulfoxide and methanol.

Aplicaciones

Yohimbine hydrochloride is an α2-adrenergic receptor antagonist. It blocks the central α2-adrenegic receptors in the brain, thus preventing and reducing the effects of xylazine, an α2-adrenergic agonist. The sedative effects and respiratory depression that accompany xylazine administration are both antagonized and reversed by yohimbine. Yohimbine hydrochloride also produces an antidiuretic effect, and increases heart rate and blood pressure.

Notas

Light Sensitive, store in dark. Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Referencias documentales

W Zhang and G M Roomans. A yohimbine-dependent, UK14,304 induced ion transient in HT29 cells studied by X-ray microanalysis. Scanning microscopy, 1996, 10(1), 293-299.

Susan X. Jiang et. al. Reversible inhibition of intracellular calcium influx through NMDA receptors by imidazoline I2receptor antagonists. European Journal of Pharmacology, 2010,629,(1), 12-19.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H300-H310-H330

Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.

Indicaciones de precaución: P260-P284-P301+P310-P304+P340-P320-P330-P361-P302+P350-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Remove/Take off immediately all contaminated clothing. IF ON SKIN: Gently wash with plenty of soap and water. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,10102
Clase de peligro
6.1
Grupo de embalaje
II
Código de tarifa arancelaria unificado
2939.99
TSCA
Yes
RTECS
ZG1015000

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