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39562-70-4 - Nitrendipine - J60841 - Alfa Aesar

J60841 Nitrendipine

Número CAS
39562-70-4
Nombre Alternativo

Tamaño Precio ($) Cantidad Disponibilidad
100mg 56,01
500mg 234,90
1g 543,00
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Nitrendipine

MDL
MFCD00082255
EINECS
254-513-1

Propiedades químicas

Fórmula
C18H20N2O6
Peso molecular
360.36
Formulario
Powder
Solubilidad
Soluble in DMSO (17.5 mg/ml), methanol (15 mg/ml), ethyl acetate, and ethanol (25 mM). Insoluble in water.

Aplicaciones

Nitrendipine modulates NMDA receptor channel function in mammalian neurons. Nitrendipine has been shown to inhibit neutrophil adhesion to vascular endothelium. It is used in the treatment of primary hypertension to decrease blood pressure. Nitrendipine is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina.

Notas

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Referencias documentales

X Chen et. al.Quantitative determination of nitrendipine and its metabolite dehydronitrendipine in human plasma using liquid chromatography-tandem mass spectrometry.. Biomedical Chromatography. 2001, 15 (8), 518-524 .

J Muntwyler and F Follath.Calcium channel blockers in treatment of hypertension.. Progress in Cardiovascular Diseases. 2001, 44 (3), 207-216.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H302-H312-H332

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.

Indicaciones de precaución: P261-P280-P264-P270-P304+P340-P301+P312-P312-P363-P322-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Specific measures (see label). Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,6576
Código de tarifa arancelaria unificado
2933.39
TSCA
No
RTECS
US5653000

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