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4474-91-3 - Angiotensin II (human) - H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH acetate salt - J60866 - Alfa Aesar

J60866 Angiotensin II (human)

Número CAS
4474-91-3
Nombre Alternativo
H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH acetate salt

Tamaño Precio ($) Cantidad Disponibilidad
5mg 48,41
25mg 165,83
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Angiotensin II (human)

MDL
MFCD00133092

Propiedades químicas

Fórmula
C50H71N13O12
Peso molecular
1046.19
Formulario
Powder
Solubilidad
Soluble in Water (25 mg/ml), and 5% Acetic Acid (1 mg/ml).

Aplicaciones

Ang II stimulates angiogenesis and increases microvessel density. In addition, the renin-angiotensin and nitric oxide-generating systems appear to interract in the regulation of cardiovascular function. Angiotensin (Ang) II is a peptide which plays an important role in the regulation of blood pressure and has strong vasoconstrictive effects. It also stimulates the release of aldosterone from the adrenal gland and inhibits adenylate cyclase activity. It also increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase (MYLK). It also elicits an increase in voltage-dependent delayed rectifier K+ current in neurons and activates JAK2 in smooth muscle cells.

Notas

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20°C. keep away from Strong acids, Strong bases .

Referencias documentales

Caroline Cheng et. Al. Angiotensin II (ATII)-mediated hypertension increases the risk for acute coronary events, which may be caused by augmented collagen degradation. Interstitial fibers of collagen type I in the plaque can be degraded by MMP8 and MMP13 specifically. Atherosclerosis . 2009, 204,(1), 26-33.

Hsiang-Hao Hsu et. Al. Mechanisms of angiotensin II signaling on cytoskeleton of podocytes. Journal of Molecular Medicine . 2008, 86,(12), 1379-1394.

Otras referencias

Código de tarifa arancelaria unificado
2937.19
TSCA
No
RTECS
BW2165000

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