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130-61-0 - Thioridazine hydrochloride - J60895 - Alfa Aesar

J60895 Thioridazine hydrochloride

Número CAS
130-61-0
Nombre Alternativo

Tamaño Precio ($) Cantidad Disponibilidad
5g 56,20
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Thioridazine hydrochloride

MDL
MFCD00012655
EINECS
204-992-8

Propiedades químicas

Fórmula
C21H26N2S2•HCl
Peso molecular
407.03
Formulario
Powder
Punto de fusión
161-163°
Sensibilidad
Light Sensitive & Hygroscopic
Solubilidad
Soluble in water (75 mM), DMSO (100 mM), chloroform, ethanol, and methanol.

Aplicaciones

Thioridazine is a piperidine typical antipsychotic drug belonging to the phenothiazine widely used in the treatment of schizophrenia and psychosis. It primary use in medicine was the treatment of schizophrenia.This medication is used to treat certain mental/mood disorders (e.g., schizophrenia). Thioridazine·HCl is a calcium channel protein inhibitor as well as a D2DR/D4DR inhibitor. It is an intercalating agent for analyzing the integrity of double stranded DNA by using the square-wave voltammetry.

Notas

Light Sensitive & Hygroscopic. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, light, water, moisture.

Referencias documentales

H. Garfield Kelly,; J. E. Fay,; S. G. Laverty.Thioridazine Hydrochloride (Mellaril): Its Effect on the Electrocardiogram and a Report of Two Fatalities with Electrocardiographic Abnormalities. Can Med Assoc J. 1963, 89 (11), 546-554.

John R. Huston, MD; George E. Bell, MD.The Effect of Thioridazine Hydrochloride and Chlorpromazine on the Electrocardiogram. JAMA. 1966, 198 (1), 16-20..

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,9359
Clase de peligro
9
Grupo de embalaje
III
Código de tarifa arancelaria unificado
2934.30
TSCA
No
RTECS
SP2275000

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