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86386-73-4 - Fluconazole, 99% - J62015 - Alfa Aesar

J62015 Fluconazole, 99%

Número CAS
86386-73-4
Nombre Alternativo

Fluconazole, 99%

MDL
MFCD00274549

Propiedades químicas

Fórmula
C13H12F2N6O
Peso molecular
306.27
Formulario
Crystalline powder
Punto de fusión
138-140°
Densidad
1.05
Solubilidad
Soluble indimethylsulfoxide and ethanol.

Aplicaciones

Fluconazole is used to treat a variety of fungal infections, especially Candida infections of the vagina (yeast infections), mouth, throat and bloodstream. It is also used by the people having weak immune system such as persons with neutropenia due to cancer chemotherapy, transplanted patients and premature infants.

Notas

Incompatible with oxidizing agents.

Referencias documentales

Matsui, K.; Tsume, Y.; Amidon, G. E.; Amidon, G. L. In Vitro Dissolution of Fluconazole and Dipyridamole in Gastrointestinal Simulator (GIS), Predicting in Vivo Dissolution and Drug-Drug Interaction Caused by Acid-Reducing Agents. Mol. Pharmaceutics. 2015, 12 (7), 2418-2428.

Bhardwaj, T.; Bhardwaj, V.; Sharma, K.; Gupta, A.; Cameotra, S. S.; Sharma, P. Thermo-acoustical analysis of sodium dodecyl sulfate: Fluconazole (antifungal drug) based micellar system in hydro-ethanol solutions for potential drug topical application. J. Chem. Thermodyn. 2014, 78, 1-6.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,4122
Código de tarifa arancelaria unificado
2933.99
TSCA
No
RTECS
XZ4810000

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