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70-18-8 - L-Glutathione, reduced, 98+% - gamma-L-Glutamyl-L-cysteinylglycine - GSH - J62166 - Alfa Aesar

J62166 L-Glutathione, reduced, 98+%

Número CAS
70-18-8
Nombre Alternativo
gamma-L-Glutamyl-L-cysteinylglycine
GSH

Tamaño Precio ($) Cantidad Disponibilidad
5g 41,90
25g 115,00
100g 388,00
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L-Glutathione, reduced, 98+%

MDL
MFCD00065939
EINECS
200-725-4

Propiedades químicas

Fórmula
C10H17N3O6S
Peso molecular
307.33
Formulario
Crystalline powder
Punto de fusión
ca 193° dec.
Solubilidad
Soluble in water, dimethyl formamide, ethanol, phosphate buffered saline, diluted alcohol, liquid ammonia and dimethyl sulfoxide.

Aplicaciones

A tripeptide used for the reductive cleavage of disulfide bonds L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca2+ ions. It is also used in white wine production.

Notas

Store in cool place. Incompatible with strong oxidizing agents.

Referencias documentales

Deheshi, S.; Dabiri, B.; Fan, S.; Tsang, M.; Rintoul, G. L. Changes in mitochondrial morphology induced by calcium or rotenone in primary astrocytes occur predominantly through ros-mediated remodeling. J. Neurochem. 2015, 133 (5), 684-699.

Li, X.; Zheng, L.; Wang, Y.; Zhang, N.; Lou, Y.; Xiao, T.; Liu, J. A novel electrocatalyst with high sensitivity in detecting glutathione reduced by 2-hydroxypropyl- β-cyclodextrin enveloped 10-methylphenothiazine. RSC Adv. 2015, 5 (88), 71749-71755.

Otras referencias

Merck
14,4475
Beilstein
1729812
Código de tarifa arancelaria unificado
2930.90
TSCA
Yes
RTECS
MC0556000

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