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88150-42-9 - Amlodipine, 97+% - UK-48340 - J62242 - Alfa Aesar

J62242 Amlodipine, 97+%

Número CAS
88150-42-9
Nombre Alternativo
UK-48340

Tamaño Precio ($) Cantidad Disponibilidad
1g 105,00
5g 404,00
10g 527,00
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Amlodipine, 97+%

MDL
MFCD00864687
EINECS
425-820-1

Propiedades químicas

Fórmula
C20H25ClN2O5
Peso molecular
408.88
Formulario
Crystalline powder
Punto de fusión
134-136°
Solubilidad
Soluble in dimethyl sulfoxide, ethanol, water, dimethyl formamide, acetone, chloroform, ethyl acetate and methanol.

Aplicaciones

A calcium channel antagonist with potent antioxidant activityAmlodipine is an L-type calcium channel protein inhibitor and blocker. It is used in combination with the angiotensin receptor blocker olmesartan. Further, it acts as a dihydropyridine calcium channel blocker. It is used as an anti-hypertensive. It is involved in the treatment of angina and to lower blood pressure. In addition to this, it is used to prevent chest pain and in coronary artery disease.

Notas

Incompatible with oxidizing agents.

Referencias documentales

Akamine, Y.; Uehara, H.; Miura, M.; Yasui-Furukori, N.; Uno, T. Multiple inductive effects of carbamazepine on combined therapy with paliperidone and amlodipine. J. Clin. Pharm. Ther. 2015, 40 (4), 480-482.

Norouzi, P.; Gupta, V. K.; Larijani, B.; Rasoolipour, S.; Faridbod, F.; Ganjali, M. R. Coulometric differential FFT admittance voltammetry determination of Amlodipine in pharmaceutical formulation by nano-composite electrode. Talanta 2015, 131, 577-584.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H301-H318-H373-H400-H410

Toxic if swallowed. Causes serious eye damage. May cause damage to organs through prolonged or repeated exposure. Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects.

Indicaciones de precaución: P260-P273-P280-P264-P301+P310-P305+P351+P338-P310-P321-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,491
Clase de peligro
6.1
Grupo de embalaje
III
Código de tarifa arancelaria unificado
2933.39
TSCA
No
RTECS
US7968329

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