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446-86-6 - Azathioprine - 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine - J62314 - Alfa Aesar

J62314 Azathioprine

Número CAS
446-86-6
Nombre Alternativo
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine

Tamaño Precio ($) Cantidad Disponibilidad
1g 76,10
5g 280,00
10g 534,00
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Azathioprine

MDL
MFCD00069203
EINECS
207-175-4

Propiedades químicas

Fórmula
C9H7N7O2S
Peso molecular
277.26
Formulario
Crystalline powder
Solubilidad
Soluble in Dichloromethane and dimethyl sulfoxide.

Aplicaciones

Azathioprine is an immunosuppressive purine antimetabolite. The mechanism of action of azathioprine is as a nucleic acid synthesis inhibitor. It has shown promise in treatment of alopecia areata (autoimmune hair loss), with no difference in effectiveness between genders.

Notas

Store at -20°C. Incompatible with oxidizing agents. Protect from heat.

Referencias documentales

W.R. Connell.; Kamm.; Ritchie.; Prof J.E. Lennard-Jones.; Dickson.; A.M. Balkwill. Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease.The Lancet. 1994, 343 (8908),1249-1252 .

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H350-H302-H315-H319-H335

May cause cancer. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P201-P261-P280-P281-P305+P351+P338-P304+P340-P362-P301+P312-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,902
Código de tarifa arancelaria unificado
2933.59
TSCA
No
RTECS
UO8925000

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