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51481-61-9 - Cimetidine, 98+% - 1-Cyano-3-methyl-2-[2-(5-methyl-4-imidazolylmethylthio)ethyl]guanidine - SKF-92334 - J62825 - Alfa Aesar

J62825 Cimetidine, 98+%

Número CAS
51481-61-9
Nombre Alternativo
1-Cyano-3-methyl-2-[2-(5-methyl-4-imidazolylmethylthio)ethyl]guanidine
SKF-92334

Tamaño Precio ($) Cantidad Disponibilidad
5g 80,55
10g 101,00
25g 175,20
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Cimetidine, 98+%

MDL
MFCD00133296
EINECS
257-232-2

Propiedades químicas

Fórmula
C10H16N6S
Peso molecular
252.34
Formulario
Powder
Punto de fusión
139-144°
Solubilidad
Soluble to 50 mM in water and to 100 mM in DMSO, solubility in HCl (almost transparency).

Aplicaciones

Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the growth of several tumors, including gastrointestinal cancer. This compound is an anti-angiogenic agent and is an activator of Nischarin. Competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output

Notas

Store away from heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Referencias documentales

Yasui-Furukori N, et al. Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics.Clinical pharmacology and therapeutics.,2005,77(1), 17-23.

Yoshizawa F, et al. Time course of leucine-induced 4E-BP1 and S6K1 phosphorylation in the liver and skeletal muscle of rats.Journal of clinical pharmacology.,1981,21(2), 87-91.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H360-H303

May damage fertility or the unborn child. May be harmful if swallowed.

Indicaciones de precaución: P201-P281-P202-P312-P308+P313-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Do not handle until all safety precautions have been read and understood. Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,2279
Código de tarifa arancelaria unificado
2933.29
TSCA
No
RTECS
MF0035500

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