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1177-87-3 - Dexamethasone acetate - J63691 - Alfa Aesar

J63691 Dexamethasone acetate

Número CAS
1177-87-3
Nombre Alternativo

Tamaño Precio ($) Cantidad Disponibilidad
250mg 52,50
1g 172,00
5g 636,00
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Dexamethasone acetate

MDL
MFCD00027407
EINECS
214-646-8

Propiedades químicas

Fórmula
C24H31FO6
Peso molecular
434.50
Formulario
Powder
Punto de fusión
240°
Solubilidad
Soluble at 100 mg/ml in acetone

Aplicaciones

Dexamethasone has many uses in the treatment of cancer. Dexamethasone relieves inflammation in various parts of the body. To treat or prevent allergic reactions. As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions. As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It is also used for replacement therapy in adrenal insufficiency and in a screening test for the diagnosis of cushing's syndrome. Dexamethasone Acetate has also been determined to markedly decrease the number of activated macrophages. In addition, Dexamethasone Acetate has been observed to significantly decrease mRNA levels of TPH2 (tryptophan hydroxylase-2) in the raphe nuclei of C57/Bl6 mice.

Notas

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.

Referencias documentales

Leibowitz HM,; Kupferman A,; Stewart RH,; Kimbrough RL.Evaluation of dexamethasone acetate as a topical ophthalmic formulation. . Am J Ophthalmol. . 1978, 86 (3), 418-23..

Roberts CP,; Murphy AA,; Santanam N,; Parthasarathy S. The effect of RU 486 and related compounds on cultured macrophage differentiation and function. Am J Obstet Gynecol.. 1996, 175 (2), 248-57.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H317

May cause an allergic skin reaction.

Indicaciones de precaución: P261-P280-P272-P363-P321-P333+P313-P302+P352-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Contaminated work clothing should not be allowed out of the workplace. Wash contaminated clothing before reuse. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. IF ON SKIN: Wash with plenty of soap and water. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,2943
Beilstein
2342608
Código de tarifa arancelaria unificado
2937.22
TSCA
Yes
RTECS
TU4050000

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