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7421-40-1 - Carbenoxolone disodium salt, 97+% - J63714 - Alfa Aesar

J63714 Carbenoxolone disodium salt, 97+%

Número CAS
7421-40-1
Nombre Alternativo

Tamaño Precio ($) Cantidad Disponibilidad
1g 34,71
5g 113,20
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Carbenoxolone disodium salt, 97+%

MDL
MFCD00079043
EINECS
231-044-0

Propiedades químicas

Fórmula
C34H48Na2O7
Peso molecular
614.70
Formulario
Solid
Solubilidad
Soluble in water to 100 mM.

Aplicaciones

Carbenoxolone is anti-inflammatory. It is often used as a gap junction inhibitor in neuroscience research. Carbenoxolone is also an inhibitor of the steroid dehydrogenase enzymes 11 β-hydroxysteroid dehydrogenase (human) and 3α, 20 β-hydroxysteroid dehydrogenase (bacterial). It is used for the treatment of digestive tract ulcers, especially in the stomach. Used in the treatment of peptic, mainly gastric, ulcers. It is often used as a gap junction inhibitor in neuroscience research.

Notas

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from heat.

Referencias documentales

L. Horwich,; R. Galloway.Treatment of gastric ulceration with carbenoxolone sodium: clinical and radiological evaluation.. Br Med J. . 1965 , 2 (5473), 1274-1277..

W. Hausmann,; A. L. Tarnoky. Biochemical Effects Of Short-Term Treatment With Carbenoxolone Disodium. British Journal of Pharmacology and Chemotherapy. 1966, 26 (2) , 412-420.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H315-H319-H335-H303

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May be harmful if swallowed.

Indicaciones de precaución: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,1793
Código de tarifa arancelaria unificado
2918.99
TSCA
No
RTECS
RK0250000

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