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303-45-7 - Gossypol, 98+% - Thespesin - 2,2'-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) - J63767 - Alfa Aesar

J63767 Gossypol, 98+%

Número CAS
303-45-7
Nombre Alternativo
Thespesin
2,2'-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene)

Tamaño Precio ($) Cantidad Disponibilidad
25mg 59,60
100mg 116,00
250mg 232,00
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Gossypol, 98+%

MDL
MFCD00017352

Propiedades químicas

Fórmula
C30H30O8
Peso molecular
518.56
Formulario
Powder
Solubilidad
Soluble in 100%ethanol (25 mg/ml), DMF (25 mg/ml), acetone, DMSO (25 mM), methanol (2 mg/ml), ether, chloroform, sodium carbonate, and dilute aqueous solutions of ammonia . Insoluble in water. Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor, anitviral, and antioxidant properties.

Aplicaciones

Gossypol acts as an inhibitor for several dehydrogenase enzymes. Gossypol has also long been known to possess antimalarial properties. Gossypol provided reliable contraception. gossypol provokes infertility and causes spermatogenesis. Gossypol is used as an active antifertility agent in a variety of male animals, including mice, rats, hamsters, monkeys, rabbits, and bulls.

Notas

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Referencias documentales

M.C. Chang,; Zhiping Gu (Chi-ping Ku),; S.K. Saksena. Effects of Gossypol on the fertility of male rats, hamsters and rabbits. Contraception. 1980, 21(5), 461-469.

Ying-Bo Mao,; Wen-Juan Cai,; Jia-Wei Wang,; Gao-Jie Hong. Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypo. Nature Biotechnology. 2007 , 251307 - 1313 .

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H341-H361-H302

Suspected of causing genetic defects. Suspected of damaging fertility or the unborn child. Harmful if swallowed.

Indicaciones de precaución: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,4528
Código de tarifa arancelaria unificado
2912.49
TSCA
No
RTECS
DU3100000

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