Cookies disclaimer

Estoy de acuerdo utilizamos cookies para mejorar la experiencia de navegación del usuario y para estudiar cómo se utiliza nuestro sitio web. si navega por nuestro sitio web, estará aceptando el uso de las cookies en las condiciones establecidas en la presente política de cookies. esta política puede ser actualizada, por lo que le invitamos a revisarla de forma regular

Apolipoprotein A-I, human plasma, 95%, BT-927 - Apo A-I - J64506 - Alfa Aesar

J64506 Apolipoprotein A-I, human plasma, 95%, BT-927

Número CAS
Nombre Alternativo
Apo A-I

Tamaño Precio ($) Cantidad Disponibilidad
1mg 189,52
Añadir al carrito Añadir al presupuesto al por mayor Ver artículo

Apolipoprotein A-I, human plasma, 95%, BT-927

MDL
MFCD00132610

Propiedades químicas

Formulario
Aqueous solution
Solubilidad
Immiscible with water.

Aplicaciones

The Apo-AI protein promotes fat efflux, including cholesterol, from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathicamyloidosis. Apo A-I was also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect.Apolipoprotein A-I, human plasma is activated lecithin-cholesterol (LCAT) acyltransferase, which is responsible for cholesterol esterification in plasma. Further, it is a major protein component in high density lipoprotein.

Notas

Supplied at 1mg/ml in 10mM ammonium bicarbonate buffer, pH 7.4. Store at -20°C and stable for up to 6 months.Incompatible with strong oxidizing agents.

Referencias documentales

Franceschini, G.; Sirtori, M.; Gianfranceschi, G.; Sirtori, C. R. Relation between the HDL apoproteins and A-I isoproteins in subjects with the AIMilano abnormalityMetab. Clin. Exp. 1981, 30 (5), 502-509.

Mendivil, C. O.; Furtado, J.; Morton, A. M.; Wang, L.; Sacks, F. M. Novel Pathways of Apolipoprotein A-I Metabolism in High-Density Lipoprotein of Different Sizes in Humans. Arterioscler. Thromb. Vasc. Biol. 2016, 36 (1), 156-165.

Handa, D.; Kimura, H.; Oka, T.; Takechi, Y.; Okuhira, K.; Phillips, M. C.; Saito, H. Kinetic and Thermodynamic Analyses of Spontaneous Exchange between High-Density Lipoprotein-Bound and Lipid-Free Apolipoprotein A-I. Biochemistry 2015, 54 (4), 1123-1131.

Otras referencias

Código de tarifa arancelaria unificado
2937.19
TSCA
No

Recomendado

  • J63134

    TRIS, 0.5M buffer soln., pH 9.5
  • B20068

    1-Methylsulfonyl-4-nitrobenzene, 97%
  • 45091

    Platinum foil, 0.203mm (0.008in) thick, 99.9% (metals basis)
  • 40359

    Sulfur in Heavy Mineral Oil standard solution, Specpure®, 30,000µg/g (3.00%)
  • B21981

    4-Allyl-2,6-dimethoxyphenol, 98%

Visto recientemente

Productos químicos

Ciencias de la vida

Metales & materiales

Catalizadores

Análisis y material de laboratorio