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3483-12-3 - 1,4-Dithio-DL-threitol, Electrophoresis Grade, 99% - Cleland's Reagent DTT racemic - (±)-threo-1,4-Dimercapto-2,3-butanediol - J64545 - Alfa Aesar

J64545 1,4-Dithio-DL-threitol, Electrophoresis Grade, 99%

Número CAS
3483-12-3
Nombre Alternativo
Cleland's Reagent DTT racemic
(±)-threo-1,4-Dimercapto-2,3-butanediol

Tamaño Precio ($) Cantidad Disponibilidad
1g 34,00
5g 91,60
25g 369,00
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1,4-Dithio-DL-threitol, Electrophoresis Grade, 99%

MDL
MFCD00004877
EINECS
222-468-7

Propiedades químicas

Fórmula
C4H10O2S2
Peso molecular
154.25
Formulario
Powder
Punto de fusión
40-43°
Punto de ebullición
125-130°/12mm
Punto de inflamabilidad
>110°(230°F)
Sensibilidad
Air Sensitive
Solubilidad
Soluble in water, ethanol, chloroform, diethyl ether, acetone, ether and ethyl acetate.

Aplicaciones

1,4-Dithio-DL-threitol is used as a protective agent for preventing oxidation of thiol groups and reagent for the reduction of disulfide groups in proteins. It is employed to investigate a-ketoglutarate dehydrogenase function, flavin cofactors in proteins and protein moieties involved in peroxide reduction. It is also useful for stabilizing sulfhydryl-containing enzymes.

Notas

Air and heat sensitive. Hygroscopic. Incompatible with strong oxidizing agents, reducing agents and alkalies.

Referencias documentales

Tobolkina, E.; Salazar, F. C.; Qiao, L.; Girault, H. H. Protein/peptide purification by three-well OFFGEL electrophoresis with immobilized ultra narrow pH gradient gels. 2014, 6 (12), 3995-4002.

Fujita, K.; Muraki, T.; Sakurai, T.; Oishi, A.; Taguchi, Y. Synthesis of Novel Dendritic α-Glycol Ligands Derived from DL-Dithiothreitol and Their Application to Ring-opening Polymerization of ε-Caprolactone. Chem. Lett. 2004, 34 (8), 1180-1181.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,3376
Beilstein
1719757
Código de tarifa arancelaria unificado
2930.90
TSCA
Yes
RTECS
EK1610000

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