Cookies disclaimer

Estoy de acuerdo utilizamos cookies para mejorar la experiencia de navegación del usuario y para estudiar cómo se utiliza nuestro sitio web. si navega por nuestro sitio web, estará aceptando el uso de las cookies en las condiciones establecidas en la presente política de cookies. esta política puede ser actualizada, por lo que le invitamos a revisarla de forma regular

42155-08-8 - 2'-Deoxyuridine-5'-monophosphate disodium salt, 99% - 2'-dUMP - 2'-Deoxyuridine-5'-monophosphoric acid disodium salt - J64627 - Alfa Aesar

J64627 2'-Deoxyuridine-5'-monophosphate disodium salt, 99%

Número CAS
42155-08-8
Nombre Alternativo
2'-dUMP
2'-Deoxyuridine-5'-monophosphoric acid disodium salt

Tamaño Precio ($) Cantidad Disponibilidad
250mg 85,70
1g 172,00
Añadir al carrito Añadir al presupuesto al por mayor Ver artículo

2'-Deoxyuridine-5'-monophosphate disodium salt, 99%

MDL
MFCD00065282
EINECS
255-687-1

Propiedades químicas

Fórmula
C9H11N2Na2O8P
Peso molecular
352.15
Formulario
Powder
Solubilidad
Soluble in water.

Aplicaciones

2?-Deoxyuridine 5?-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) (EC 2.1.1.45) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of dUMP analogues in potential chemotherapy applications.

Notas

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Referencias documentales

Ruth L. Saxl.; James Reston.; Zhe Nie.; Thomas I. Kalman.; Frank Maley. Modification of Escherichia coli Thymidylate Synthase at Tyrosine-94 by 5-Imidazolylpropynyl-2‘-deoxyuridine 5‘-Monophosphate. Biochemistry. 2003, 42 (15), 4544-4551.

Mikhail V. Rekharsky.; Asao Nakamura.; Guy A. Hembury.; Yoshihisa Inoue. Thermodynamic Study of the Discrimination between Uridine and Thymidine Derivatives by Hydrophobic, Stacking, and Intercalating Interactions. Bulletin of the Chemical Society of Japan. 2001, 74 (3), 449-457.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Código de tarifa arancelaria unificado
2934.99
TSCA
No

Recomendado

  • L01918

    5,6-Dihydrouracil, 97%
  • J64402

    2'-Deoxyadenosine-5'-monophosphate, 98%
  • J65244

    2'-Deoxycytidine-5'-monophosphate, 99%

Visto recientemente

Productos químicos

Ciencias de la vida

Metales & materiales

Catalizadores

Análisis y material de laboratorio