Cookies disclaimer

Estoy de acuerdo utilizamos cookies para mejorar la experiencia de navegación del usuario y para estudiar cómo se utiliza nuestro sitio web. si navega por nuestro sitio web, estará aceptando el uso de las cookies en las condiciones establecidas en la presente política de cookies. esta política puede ser actualizada, por lo que le invitamos a revisarla de forma regular

1428-67-7 - Diarylpropionitrile - DPN - 2,3-Bis(4-hydroxyphenyl)-propionitrile - J65207 - Alfa Aesar

J65207 Diarylpropionitrile

Número CAS
1428-67-7
Nombre Alternativo
DPN
2,3-Bis(4-hydroxyphenyl)-propionitrile

Este elemento no se puede pedir en este momento. Vuelva a intentarlo más adelante.

Añadir al presupuesto al por mayor

Diarylpropionitrile

MDL
MFCD01695412

Propiedades químicas

Fórmula
C15H13NO2
Peso molecular
239.27
Formulario
Powder
Solubilidad
Soluble in 1eq. NaOH (30 mM), ethanol (100 mM), DMSO (100 mM), DMF (~30 mg/ml), and water (0.5 mg/ml at 25°C).

Aplicaciones

DPN protects WT and ARKO mice and significantly decreases IL-1β following LPS treatment in young adult-derived microglia. DPN also elevates Bax expression. DPN induces a dose-dependent increase on vitellogenin synthesis. PPT and DPN are effective in dynamically, but differentially regulating intracellular calcium signaling in hippocampal neurons. DPN is more efficacious than PPT in potentiating a physiological concentration of glutamate-induced intracellular Ca2+ rise in these neurons. DPN prevents the development of prostatic hyperplasia and inflammation in testosterone-treated LuRKO mice.

Notas

Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat. Store in refrigerator.

Referencias documentales

Danielle K Lewis; Adam B Johnson; Shannon Stohlgren; Ashley Harms; Farida Sohrabji; Danielle K. Lewis; Adam B. Johnson; Shannon Stohlgren; Ashley Harms; Farida Sohrabji. Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats. Journal of Neuroimmunology. 2008, 195, (1), 47-59.

Inna Meltser; Yeasmin Tahera; Evan Simpson; Malou Hultcrantz; Konstantina Charitidi; Jan-Ake Gustafsson; and Barbara Canlon. Estrogen receptor β protects against acoustic trauma in mice. J Clin Invest. 2008, 118, (4), 1563-1570.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H400-H319

Very toxic to aquatic life. Causes serious eye irritation.

Indicaciones de precaución: P273-P280-P264-P305+P351+P338-P337+P313-P391-P501a

Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Collect spillage. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Clase de peligro
9
Grupo de embalaje
III
Código de tarifa arancelaria unificado
2926.90
TSCA
No
RTECS
UG0900000

Recomendado

  • 42759

    Tris(diethylamino)gallium(III), 99.9% (metals basis)
  • H61101

    N-Boc-L-valine methyl ester, 97%
  • A14060

    1,5-Diphenylcarbazide, 97+%
  • H50490

    3-Methoxy-4-n-propoxybenzaldehyde
  • A10622

    1-Nitroso-2-naphthol, 99%

Visto recientemente

Productos químicos

Ciencias de la vida

Metales & materiales

Catalizadores

Análisis y material de laboratorio