Cookies disclaimer

Estoy de acuerdo utilizamos cookies para mejorar la experiencia de navegación del usuario y para estudiar cómo se utiliza nuestro sitio web. si navega por nuestro sitio web, estará aceptando el uso de las cookies en las condiciones establecidas en la presente política de cookies. esta política puede ser actualizada, por lo que le invitamos a revisarla de forma regular

36805-97-7 - N,N-Dimethylformamide di-tert-butyl acetal, tech. 90% - L00431 - Alfa Aesar

L00431 N,N-Dimethylformamide di-tert-butyl acetal, tech. 90%

Número CAS
36805-97-7
Nombre Alternativo

Tamaño Precio ($) Cantidad Disponibilidad
5g 73,90
25g 313,00
Añadir al carrito Añadir al presupuesto al por mayor Ver artículo

N,N-Dimethylformamide di-tert-butyl acetal, tech. 90%

MDL
MFCD00015002
EINECS
253-222-7

Propiedades químicas

Fórmula
C11H25NO2
Peso molecular
203.33
Punto de ebullición
75-77°/12mm
Punto de inflamabilidad
33°(91°F)
Densidad
0.850
Índice de refracción
1.4120
Sensibilidad
Moisture Sensitive
Solubilidad
Miscible with toluene and benzene.

Aplicaciones

N,N-Dimethylformamide di-tert-butyl acetal is used as a reagent in the synthesis of (S)-2-(1-tert-butoxycarbonyl-2-{4-[2-(5-methyl-2-phenyloxazol-4-yl)ethoxy]phenyl}ethylamino)benzoic acid methyl ester, 3-O-tert-butylmorphine, tert-butylesters of pyrrole and indolecarboxylic acids. Further, it is used in the preparation of indolizines by intermolecular cyclization of picolinium salts.

Notas

Moisture sensitive. Incompatible with strong oxidizing agents and acids.

Referencias documentales

The conversion of carboxylic acids to their esters using DMF acetals (see for example, N,N-Dimethyl­formamide dimethyl­ acetal, A15350 ) can be extended to the preparation of t-butyl esters by using excess reagent in benzene or toluene as solvent: Synthesis, 135 (1983).

Gatineau, D.; Nguyen, D. H.; Hérault, D.; Vanthuyne, N.; Leclaire, J.; Giordano, L.; Buono, G. H-adamantylphosphinates as universal precursors of P-stereogenic compounds. J. Org. Chem. 2015, 80 (8), 4132-4141.

Hoecker, J.; Liffert, R.; Burch, P.; Wehlauch, R.; Gademann, K. Caged retinoids as photoinducible activators: Implications for cell differentiation and neurite outgrowth. Org. Biomol. Chem. 2013, 11 (20), 3314-3321.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H226-H315-H319-H335

Flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P210-P261-P280-P240-P303+P361+P353-P305+P351+P338-P304+P340-P362-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Beilstein
969629
Clase de peligro
3
Grupo de embalaje
III
Código de tarifa arancelaria unificado
2922.50
TSCA
No

Recomendado

Visto recientemente

Productos químicos

Ciencias de la vida

Metales & materiales

Catalizadores

Análisis y material de laboratorio