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3554-74-3 - 3-Hydroxy-1-methylpiperidine, 98% - 1-Methyl-3-piperidinol - L10829 - Alfa Aesar

L10829 3-Hydroxy-1-methylpiperidine, 98%

Número CAS
3554-74-3
Nombre Alternativo
1-Methyl-3-piperidinol

Tamaño Precio ($) Cantidad Disponibilidad
5g 17,77
25g 59,40
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3-Hydroxy-1-methylpiperidine, 98%

MDL
MFCD00006495
EINECS
222-609-2

Propiedades químicas

Fórmula
C6H13NO
Peso molecular
115.18
Punto de ebullición
76-78°/11mm
Punto de inflamabilidad
70°(158°F)
Densidad
0.999
Índice de refracción
1.4740
Solubilidad
Fully misicible in water.

Aplicaciones

Reactant for Optimization of Novobiocin scaffold to produce antitumor agents, Formation of carbamates and N-alkylimidazoles. Reactant for synthesis of Pyridine derivatives as CDK5 inhibitors Phenylcarbamate derivatives as ligands for nicotinic acetylcholine receptors, Amino phosphite ligands, Mexiletine enantiomers by nucleophilic aromatic substitution.

Notas

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Referencias documentales

Huiping Zhao et. al. Engineering an antibiotic to fight cancer: optimization of the novobiocin scaffold to produce anti-proliferative agents.. Journal of medicinal and pharmaceutical chemistry,. 2007, 54 (11), 3839-3853.

Matthew R. Kaller et. al. Design and synthesis of 6-oxo-1,6-dihydropyridines as CDK5 inhibitors. Bioorganic & Medicinal Chemistry Letters. 2009, 19 (23), 6591-6594.

The Na derivative can be used in combination with Ni(OAc) 2 /NaH for desufurization of thioethers, showing dramatic rate enhancement compared with other systems: Tetrahedron Lett ., 39, 8987 (1998).

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H315-H319-H335-H227

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.

Indicaciones de precaución: P210-P261-P280-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Beilstein
103017
Código de tarifa arancelaria unificado
2933.39
TSCA
Yes

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