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7144-05-0 - 4-(Aminomethyl)piperidine, 98+% - 4-Piperidinemethylamine - L11577 - Alfa Aesar

L11577 4-(Aminomethyl)piperidine, 98+%

Número CAS
7144-05-0
Nombre Alternativo
4-Piperidinemethylamine

Tamaño Precio ($) Cantidad Disponibilidad
5g 24,64
25g 107,12
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4-(Aminomethyl)piperidine, 98+%

MDL
MFCD00006007
EINECS
230-446-3

Propiedades químicas

Fórmula
C6H14N2
Peso molecular
114.19
Punto de fusión
23-25°
Punto de ebullición
199-200°
Punto de inflamabilidad
79°(174°F)
Índice de refracción
1.4900
Sensibilidad
Air Sensitive
Solubilidad
Soluble in water.

Aplicaciones

4-(Aminomethyl)piperidine is used as a reagent for rapid cleavage of the Fmoc group in peptide synthesis, particularly recommended in conjunction with Fmoc-protected acid chlorides as the active species. It Is also used as a reactant for evaulated as a small molecule inhibitor of CD4-gp120 binding and as a reagent involved in solvothermal preparation of germanium oxide hydroxide 3D net zeotype, involved in zeolite synthesis and as a coupling agent for adhesive systems.

Notas

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is sensitive to air.

Referencias documentales

Louis A. Carpino.; Dean Sadat-Aalaee.; Michael Beyermann. Tris(2-aminoethyl)amine as substitute for 4-(aminomethyl)piperidine in the FMOC/polyamine approach to rapid peptide synthesis. J. Org. Chem. 1990, 55 (5), 1673-1675.

Michael Beyermann.; Michael Bienert.; Hartmut Niedrich.; Louis A. Carpino.; Dean Sadat-Aalaee. Rapid continuous peptide synthesis via FMOC amino acid chloride coupling and 4-(aminomethyl)piperidine deblocking. J. Org. Chem. 1990, 55 (2), 721-728.

Reagent for rapid cleavage of the Fmoc group in peptide synthesis, particularly recommended in conjunction with Fmoc-protected acid chlorides as the active species: J. Org. Chem., 55, 721 (1990). See also Tris(2-aminoethyl)­amine, B21789. See Appendix 6.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Indicaciones de precaución: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Beilstein
471185
Clase de peligro
8
Grupo de embalaje
III
Código de tarifa arancelaria unificado
2933.39
TSCA
Yes

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