Cookies disclaimer

Estoy de acuerdo utilizamos cookies para mejorar la experiencia de navegación del usuario y para estudiar cómo se utiliza nuestro sitio web. si navega por nuestro sitio web, estará aceptando el uso de las cookies en las condiciones establecidas en la presente política de cookies. esta política puede ser actualizada, por lo que le invitamos a revisarla de forma regular

57260-71-6 - 1-Boc-piperazine, 99% - 1-(tert-Butoxycarbonyl)piperazine - tert-Butyl 1-piperazinecarboxylate - L13363 - Alfa Aesar

L13363 1-Boc-piperazine, 99%

Número CAS
57260-71-6
Nombre Alternativo
1-(tert-Butoxycarbonyl)piperazine
tert-Butyl 1-piperazinecarboxylate

Tamaño Precio ($) Cantidad Disponibilidad
1g 23,22
5g 82,53
25g 321,30
Añadir al carrito Añadir al presupuesto al por mayor Ver artículo

1-Boc-piperazine, 99%

MDL
MFCD00075265

Propiedades químicas

Fórmula
C9H18N2O2
Peso molecular
186.26
Punto de fusión
44-48°
Sensibilidad
Air Sensitive
Solubilidad
Soluble in ethyl acetate, methanol and water.

Aplicaciones

1-Boc-piperazine is useful for the preparation of (m-phenoxy)phenyl substituted piperazine derivatives. It is also used in the synthesis of indazole DNA gyrase inhibitors. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also in involved in Buchwald-Hartwig coupling reactions with aryl halides.

Notas

Hygroscopic. Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.

Referencias documentales

Pd-catalyzed C-N coupling with a variety of bromoarenes, in the presence of NaO-t-Bu and Tri(o-tolyl)­phosphine, A12093, provides a route to arylpiperazines of potential pharmacological interest: Tetrahedron Lett., 39, 2219 (1998).

Ba-Salem, A. O.; Shaikh, M. N.; Ullah, N.; Faiz, M. Synthesis and magnetic relaxation properties of new Gd(III) complexes derived from DTPA-bis(amide) conjugates of arylpiperazinyl amines. Inorg. Chem. Commun. 2015, 56, 5-7.

Nemeckova-Herova, D.; Pazdera, P. A Simplified Protocol for Routine Chemoselective Syntheses of Piperazines Substituted in the 1-Position by an Electron Withdrawing Group. Curr. Org. Synth. 2015, 12 (2), 173-179.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Indicaciones de precaución: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Beilstein
879985
Código de tarifa arancelaria unificado
2933.59
TSCA
No

Recomendado

  • A10296

    Benzoin methyl ether, 97%
  • A10807

    1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%
  • A11118

    2,2'-Dipyridyl disulfide, 98%
  • A11606

    1-Propylamine, 98%
  • A14149

    1,3-Dichloroacetone, 96%

Visto recientemente

Productos químicos

Ciencias de la vida

Metales & materiales

Catalizadores

Análisis y material de laboratorio