Cookies disclaimer

Estoy de acuerdo utilizamos cookies para mejorar la experiencia de navegación del usuario y para estudiar cómo se utiliza nuestro sitio web. si navega por nuestro sitio web, estará aceptando el uso de las cookies en las condiciones establecidas en la presente política de cookies. esta política puede ser actualizada, por lo que le invitamos a revisarla de forma regular

50-91-9 - 5-Fluoro-2'-deoxyuridine, 98+% - 2'-Deoxy-5-fluorouridine - Floxuridine - L16497 - Alfa Aesar

L16497 5-Fluoro-2'-deoxyuridine, 98+%

Número CAS
50-91-9
Nombre Alternativo
2'-Deoxy-5-fluorouridine
Floxuridine

Tamaño Precio ($) Cantidad Disponibilidad
100mg 79,21
500mg 261,62
Añadir al carrito Añadir al presupuesto al por mayor Ver artículo

5-Fluoro-2'-deoxyuridine, 98+%

MDL
MFCD00006530
EINECS
200-072-5

Propiedades químicas

Fórmula
C9H11FN2O5
Peso molecular
246.20
Punto de fusión
148-151°
Solubilidad
Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform.

Aplicaciones

5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase and DNA synthesis. In addition to this, it plays an important role in the treatment of colorectal cancer.

Notas

Store in a cool place.Incompatible with strong oxidizing agents and strong bases.

Referencias documentales

Rooney, J. P.; Luz, A. L.; Gonzalez-Hunt, C. P.; Bodhicharla, R.; Ryde, I. T.; Anbalagan, C.; Meyer, J. N. Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans. Exp. Gerontol. 2014, 56, 69-76.

Kruspe, S.; Hahn, U. An Aptamer Intrinsically Comprising 5-Fluoro-2'-deoxyuridine for Targeted Chemotherapy. Mol. BioSyst. 2014, 53 (39), 10541-10544.

Indicaciones de peligro y de precaución del GHS

Indicaciones de peligro (UE): H360-H341-H302

May damage fertility or the unborn child. Suspected of causing genetic defects. Harmful if swallowed.

Indicaciones de precaución: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Otras referencias

Merck
14,4112
Beilstein
2645818
Clase de peligro
6.1
Grupo de embalaje
III
Código de tarifa arancelaria unificado
2934.99
TSCA
No
RTECS
YU7535000

Recomendado

  • A10926

    Diethylenetriaminepentaacetic acid, 98+%
  • A11079

    Sodium butyrate, 98+%
  • A12075

    Cacodylic acid, 98%
  • 11287

    Gadolinium(III) chloride hexahydrate, REacton®, 99.99% (REO)
  • 14248

    Iodine, crystalline, 99.5%

Visto recientemente

Productos químicos

Ciencias de la vida

Metales & materiales

Catalizadores

Análisis y material de laboratorio