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Apoptosis is a highly regulated programmed cell death. It is a critical part of normal cell development, immunity and wound repair. It may occur under either physiological or pathological conditions. Apoptotic cell cycles are characterized by membrane blebbing, cell shrinkage, and chromosomal DNA fragmentation. Abnormalities in apoptosis are linked to a variety of pathologies. Excess cell death can contribute to the acquired immune deficiency syndrome (AIDS) and neurodegenerative diseases like Alzheimer,s and Parkinson,s disease. Too little cell death can lead to cancer, persistent viral infection, and some autoimmune disorders. Because apoptosis is highly regulated, there are many pathways linked to apoptotic activity. Alfa Aesar provides a wide range of molecules that either inhibit or induce apoptosis through any number of the associated pathways.

  • 10058-F4
  • 2-(3-(2,3-Dichlorophenoxy)propylamino)ethanol hydrochloride
  • 2-(4,5,6,7-Tetraiodo-1,3-dioxoisoindolin-2-yl)acetic acid
  • 3',4',5,7-Tetrahydroxyflavone, 97%
  • 3-Aminobenzamide, 98%
  • 4',5,7-Trihydroxyflavone, 97%
  • 4',7-Dihydroxyisoflavone, 98+%
  • 6-Aminonicotinamide, 99%
  • 7,8-Dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • Acemetacin
  • Acivicin, 98+%
    Acivicin is an antibiotic that inhibits g-glutamyl transpeptidase and transmembrane glutathione transport. It also induces apoptosis in human lymphoblastoid cells.
  • Acridine Orange
  • Acycloguanosine, 98%
  • Alendronate sodium trihydrate, 97%
  • Alloxan monohydrate, 98%
  • Amiodarone hydrochloride
  • Anisomycin, 97%
  • Antimycin A
  • Aphidicolin
  • Apoptosis Activator 2
  • Bambuterol hydrochloride, 98+%
  • Bax Channel Blocker
  • Benzamidine hydrochloride hydrate, 99%, water ca 10-14%
  • Benzylphosphonic acid, 97%
  • Berberine chloride
  • Bezafibrate, 98+%
  • Blasticidin S hydrochloride, 98+%, 10mg/ml in 1M HEPES buffer soln.
  • Brefeldin A, 99%
  • Calyculin A, 98+%
  • Camptothecin
  • Carboplatin
  • Chelerythrine chloride, 99+%
  • Chenodeoxycholic acid
  • CI 994
  • CIL-102
  • cis-3,4',5-Trimethoxy-3'-aminostilbene
  • cis-5-(3,5-Dimethoxystyryl)-2-methoxyphenol
  • cis-Diamminedichloroplatinum(II), Pt 64.5% min
  • Clofibrate, 95+%
  • Clomiphene citrate
  • Colchicine, 98%
  • Concanavalin A
  • Cyclophosphamide monohydrate, 97+%
  • Cyproconazole
  • Dacarbazine
  • Danazol
  • D-erythro-Sphingosine, 99+%
  • Diosgenin
  • Diosmin
  • Docetaxel, 99%

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire