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147-24-0 - Diphenhydramine hydrochloride, 99% - A10136 - Alfa Aesar

A10136 Diphenhydramine hydrochloride, 99%

Numéro CAS
147-24-0
Synonymes

Dimensions Prix ($) Quantité Disponibilité
50g 26,90
250g 84,40
1000g 291,00
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Diphenhydramine hydrochloride, 99%

MDL
MFCD00012479
EINECS
205-687-2

Propriétés chimiques

Formule
(C6H5)2CHOCH2CH2N(CH3)2•HCl
Poids formulaire
291.82
Point de fusion
168-169°
Sensibilité
Light Sensitive
Solubilité
Soluble in water, dimethyl sulfoxide, dimethylformamide, methanol and ethanol.

Applications

A histamine H1 receptor antagonistDiphenhydramine hydrochloride acts as a sodium channel blocker. It is used as a histamine H1-receptor antagonist. Further, it is used as a sedative, hypnotic, antiemetic, antitussive and pruritus. It is employed in the treatment of allergic conditions. In addition to this, it is used as an active ingredient in common cold preparations.

Notes

Incompatible with strong oxidizing agents, strong acids and alkalis.

Références bibliographiques

Miao, C.; Zhang, A.; Xu, Y.; Chen, S.; Ma, F.; Huang, C.; Jia, N. An ultrasensitive electrochemiluminescence sensor for detecting diphenhydramine hydrochloride based on l-cysteine-functionalized multiwalled carbon nanotubes/gold nanoparticles nanocomposites. Sens. Actuators, B 2015, 213, 5-11.

Jengathe, S. P.; Dhondge, S. S.; Paliwal, L. J.; Tangde, V. M.; Mondal, S. Effect of sodium chloride and myo-inositol on diphenhydramine hydrochloride drug in aqueous solution at different temperatures: Volumetric and acoustic approach. J. Chem. Thermodyn. 2015, 87, 78-87.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H302-H315-H319-H351-H361-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Suspected of causing cancer. Suspected of damaging fertility or the unborn child. May cause respiratory irritation.

Mentions de prudence: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Classe de danger
6.1
Groupe d'emballage
III
Code tarifaire harmonisé
2922.19
TSCA
No

Recommandé

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Catalyseurs

Analytique et matériel de laboratoire