Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

623-33-6 - Glycine ethyl ester hydrochloride, 99% - Ethyl glycinate hydrochloride - H-Gly-OEt.HCl - A10315 - Alfa Aesar

A10315 Glycine ethyl ester hydrochloride, 99%

Numéro CAS
623-33-6
Synonymes
Ethyl glycinate hydrochloride
H-Gly-OEt.HCl

Dimensions Prix ($) Quantité Disponibilité
100g 22,45
500g 63,76
2500g 204,80
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Glycine ethyl ester hydrochloride, 99%

MDL
MFCD00012871
EINECS
210-787-4

Propriétés chimiques

Formule
CH3CH2O2CCH2NH2•HCl
Poids formulaire
139.58
Point de fusion
144-148°
Sensibilité
Hygroscopic
Solubilité
Soluble in water (>1000 mg/ml at 20°C), ethanol, DMSO, and methanol.

Applications

Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.

Notes

Hygroscopic. Store away from oxidizing agents and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect from humidity.

Références bibliographiques

Zhang, H, et al. Mass spectrometry-based carboxyl footprinting of proteins: method evaluation.Int. J. Mass Spectrom.,2012,31278-86.

Bill Morandi, et al. Iron-Catalyzed Cyclopropanation with Glycine Ethyl Ester Hydrochloride in Water.Org. Lett.,2012,14(8), 2162-2163.

Reacts with ß-diketones to give substituted pyrrole-2-carboxylic esters: Synthesis, 157 (1982):

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H318

Causes serious eye damage.

Mentions de prudence: P280-P305+P351+P338-P310

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.

Autres références

Beilstein
3594034
Code tarifaire harmonisé
2922.49
TSCA
Yes
RTECS
MC0525000

Recommandé

  • A11766

    Allyl bromide, 99%, stab. with 300-1000ppm Propylene oxide
  • A12178

    Maleic anhydride, 98+%
  • A14547

    p-Toluenesulfonyl chloride, 98%
  • A18668

    Sodium nitrite, 98%
  • 14244

    Sodium nitrite, ACS, 97% min

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire