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91-02-1 - 2-Benzoylpyridine, 99% - Phenyl 2-pyridyl ketone - A10857 - Alfa Aesar

A10857 2-Benzoylpyridine, 99%

Numéro CAS
91-02-1
Synonymes
Phenyl 2-pyridyl ketone

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2-Benzoylpyridine, 99%

MDL
MFCD00006300
EINECS
202-034-3

Propriétés chimiques

Formule
C12H9NO
Poids formulaire
183.21
Point de fusion
41-45°
Point d'ébullition
313°
Point d'éclair
167°(332°F)
Densité
1.16
Solubilité
Soluble in methanol. Insoluble in water.

Applications

The Schiff bases(2-Benzoylpyridine ) and copper(II) complexes display moderate antifungal activities. 2-Benzoylpyridine is an aromatic substituent which has selective antiproliferative effects, with the majority having greater antineoplastic activity. Reaction of 2-benzoylpyridine N(4)-phenyl thiosemicarbazone (HL) with a variety of copper salts yielded a series of copper(II) complexes of the type [CuLX]. Complexes of 2-benzoylpyridine thiosemicarbazone (H2Bz4DH) as well as of its N(4)-methyl (H2Bz4Me) and N(4)-phenyl (H2Bz4Ph) analogues with iron(II), nickel(II) and zinc(II) were characterized by a variety of spectroscopic techniques.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Références bibliographiques

Angel A. Recio Despaigne,; Jeferson G. Da Silva, Ana Cerúlia M. Do Carmoa, Oscar E. Pirob, Eduardo E. Castellanoc, Heloisa Beraldoa, .Copper(II) and zinc(II) complexes with 2-benzoylpyridine-methyl hydrazone. Journal of Molecular Structure. 2009, 920 (1-3), 97-102.

M.E. Hossaina,; M.N. Alam,; J. Begum,; M. Akbar Ali,; M. Nazimuddin,; F.E. Smith,; R.C. Hynes.The preparation, characterization, crystal structure and biological activities of some copper(II) complexes of the 2-benzoylpyridine Schiff bases of S-methyl- and S-benzyldithiocarbazate. Inorganica Chimica Acta. 1996, 249(2), 207-213

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Beilstein
120283
Code tarifaire harmonisé
2933.39
TSCA
Yes
RTECS
OB6400000

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