Consentement d'utilisation des Cookies

J'accepte. Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

127-19-5 - N,N-Dimethylacetamide, 99% - DMA - A10924 - Alfa Aesar

A10924 N,N-Dimethylacetamide, 99%

Numéro de CAS
127-19-5
Synonymes
DMA

Conditionnement Prix ($) Quantité Disponibilité
250ml 21,00
500ml 26,80
2500ml 86,20
Ajouter au panier Ajouter au devis en vrac Afficher l'article

N,N-Dimethylacetamide, 99%

MDL
MFCD00008686
EINECS
204-826-4

Propriétés chimiques

Formule
C4H9NO
Poids moleculaire
87.12
Point de fusion
-20°
Point d'ébullition
165-166°
Point d'éclair
70°(158°F)
Densité
0.940
Indice de réfraction
1.4385
Solubilité
Miscible with water, benzene, alcohol, acetone, ether, esters and ketones.

Applications

N,N-Dimethylacetamide is used as a polar solvent in organic synthesis as well as in reactions involving strong bases such as sodium hydroxide. It is also used as a solvent for fibers like polyacrylonitrile, spandex, as an excipient in drugs viz. vumon, busulfex and in the adhesive industry. It finds application as a reaction medium in the production of pharmaceuticals, agrochemicals, dyes and plasticizers. It is widely used in polymer industry due to its high solving power for high molecular-weight polymers and synthetic resins. It plays an important role as a catalyst in various reactions viz. cyclization, halogenation, cynidation, alkylation and dehydrogenation and increases the yield of main products. It is also used as an extracting agent for oil and gases, in paint removers, in the production of photo-resist stripping compounds and as booster solvent in coatings.

Notes

Hygroscopic. Incompatible with strong oxidizing agents.

Références bibliographiques

Dipolar aprotic solvent, cf N,N-Dimethyl­formamide, A13547, Dimethyl­ sulfoxide, A13280, 1-Methyl-2-pyrrolidinone, A12260.

See also Sodium hydride, 13431, for warning.

Useful solvent in halex fluorinations of chloroarenes; compare Sulfolane, A13466.

Undergoes Vilsmeier-type reactions (compare DMF), with reactive substrates, introducing an acetyl group: Chem. Ber., 97, 616 (1964).

Reacts with alkyl and aryl Grignard reagents to give methyl ketones in good yields: Synthesis, 228 (1984).

In the presence of triflic anhydride and 2,4,6-collidine, forms a highly-reactive keteniminium triflate, which undergoes a [2+2] cycloaddition reaction with terminal alkenes to give, after hydrolysis a 3-alkylcyclobutanone: J. Am. Chem. Soc., 107, 2192 (1985); Org. Synth. Coll., 8, 306 (1993):

Messaadi, A.; Salhi, H.; Das, D.; Alzamil, N. O.; Alkhaldi, M. A.; Ouerfelli, N.; Hamzaoui, A. H. A novel approach to discuss the viscosity Arrhenius behaviour and to derive the partial molar properties in binary mixtures of N, N-dimethylacetamide with 2-methoxyethanol in the temperature interval (from 298.15 to 318.15) K. Phys. Chem. Liq. 2015, 53 (4), 506-517.

Shokouhi, M.; Farahani, H.; Jenab, M. H.; Jalili, A. H. Solubility of Hydrogen Sulfide in N-Methylacetamide and N, N-Dimethylacetamide: Experimental Measurement and Modeling. J. Chem. Eng. Data 2015, 60 (3), 499-508.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H227-H312-H332-H360

Combustible liquid. Harmful in contact with skin. Harmful if inhaled. May damage fertility or the unborn child.

Mentions de prudence: P210u-P201-P261-P280-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,3227
Beilstein
1737614
Code tarifaire harmonisé
2924.19
TSCA
Yes
RTECS
AB7700000

Recommandé

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire