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89-73-6 - Salicylhydroxamic acid, 99% - 2-Hydroxybenzohydroxamic acid - A11528 - Alfa Aesar

A11528 Salicylhydroxamic acid, 99%

Numéro CAS
89-73-6
Synonymes
2-Hydroxybenzohydroxamic acid

Dimensions Prix ($) Quantité Disponibilité
10g 23,13
25g 41,49
50g 75,15
100g 141,30
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Salicylhydroxamic acid, 99%

MDL
MFCD00002110
EINECS
201-934-3

Propriétés chimiques

Formule
C7H7NO3
Poids formulaire
153.14
Point de fusion
ca 170° dec.
Solubilité
It is soluble in water.

Applications

It is widely used for a variety of roles in biology and medicine as a chelating therapy. It inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths. These compounds are used as extractants for the separation of valuable metals or minerals including copper, lead, gold, other rare earth metals and kaolin. Hydroxamic acids are also used to produce corresponding isocyanates by dehydration followed by rearrangement reaction. It is also used as a common ligand utilized in the synthesis of metallacrowns.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong bases. Stable under normal conditions.

Références bibliographiques

Curt A. Davey & Roger E. Fenna. 2.3 Å Resolution X-ray Crystal Structure of the Bisubstrate Analogue Inhibitor Salicylhydroxamic Acid Bound to Human Myeloperoxidase:? A Model for a Prereaction Complex with Hydrogen Peroxide. Biochemistry. 1996, 35, (33), 10967-10973.

Mark L. Stolowitz.; Clarence Ahlem.; Karin A. Hughes.; Robert J. Kaiser.; Edward A. Kesicki.; Guisheng Li.; Kevin P. Lund.; Steven M. Torkelson.; and Jean P. Wiley. Phenylboronic Acid-Salicylhydroxamic Acid Bioconjugates. 1. A Novel Boronic Acid Complex for Protein Immobilization. Bioconjugate Chem. 2001, 12, (2), 229-239.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H341-H315-H319-H335-H303

Suspected of causing genetic defects. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May be harmful if swallowed.

Mentions de prudence: P201-P261-P280-P281-P305+P351+P338-P304+P340-P362-P312-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,8331
Beilstein
1210520
Code tarifaire harmonisé
2928.00
TSCA
No
RTECS
VO6870000

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