Consentement d'utilisation des Cookies

J'accepte. Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

563-41-7 - Semicarbazide hydrochloride, 99% - A11668 - Alfa Aesar

A11668 Semicarbazide hydrochloride, 99%

Numéro de CAS
563-41-7
Synonymes

Conditionnement Prix ($) Quantité Disponibilité
100g 23,40
500g 67,90
2500g 263,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Semicarbazide hydrochloride, 99%

MDL
MFCD00013009
EINECS
209-247-0

Propriétés chimiques

Formule
CH4N3O•HCl
Poids moleculaire
111.53
Point de fusion
ca 176° dec.
Solubilité
Soluble in water (>100g/L).

Applications

Semicarbazide hydrochloride is used as urease substrate and MAO inhibitor. Derivatizing agent for carbonyl compounds as their semicarbazones which produces crystalline compounds with characteristic melting points. Also used in heterocyclic synthesis. Semicarbazone formation has been used to separate carbonyl compounds from mixtures by adsorption onto silica gel from a hydrocarbon solution. Regeneration is by hydrolysis with oxalic acid.

Notes

Store in cool, dry conditions in well sealed container. Store away from oxidizing agent.

Références bibliographiques

Phedias Diamandis et. al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nature Chemical Biology. 2007, 3 (5), 268-273.

Fumiko Marttila-Ichihara; Karolien Castermans; Kaisa Auvinen; Mirjam G A Oude Egbrink; Sirpa Jalkanen; Arjan W Griffioen; Marko Salmi. Small-molecule inhibitors of vascular adhesion protein-1 reduce the accumulation of myeloid cells into tumors and attenuate tumor growth in mice. Journal of Immunology. 2010, 184 (6), 3164-3173.

Derivatizing agent for carbonyl compounds as their semicarbazones. Also used in heterocyclic synthesis. Semicarbazone formation has been used to separate carbonyl compounds from mixtures by adsorption onto silica gel from a hydrocarbon solution. Regeneration is by hydrolysis with oxalic acid: Tetrahedron, 37, 843 (1981).

Other reagents for the cleavage of semicarbazones include: Amberlyst® 15 in aqueous acetone: J .Chem. Soc., Perkin 1, 2563 (1988); Dowex® 50 in aqueous suspension: J. Org. Chem., 53, 878 (1988); CuSO4 in aqueous THF: J. Prakt. Chem., 322 1063 (1980).

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280a-P301+P310a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,8444
Beilstein
3593642
Classe de danger
6.1
Groupe d'emballage
III
Code tarifaire harmonisé
2928.00
TSCA
Yes
RTECS
VT3500000

Recommandé

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire