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50-78-2 - O-Acetylsalicylic acid, 99% - 2-Acetoxybenzoic acid - A12488 - Alfa Aesar

A12488 O-Acetylsalicylic acid, 99%

Numéro CAS
50-78-2
Synonymes
2-Acetoxybenzoic acid

Dimensions Prix ($) Quantité Disponibilité
100g 17,64
500g 40,27
2500g 147,29
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O-Acetylsalicylic acid, 99%

MDL
MFCD00002430
EINECS
200-064-1

Propriétés chimiques

Formule
C9H8O4
Poids formulaire
180.15
Point de fusion
133-140°
Point d'éclair
250°(482°F)
Densité
1.400
Solubilité
Soluble in 100% ethanol (80mg/ml), DMSO (41mg/ml) or dimethyl formamide (30mg/ml); slightly soluble in Phosphate-buffered saline (PBS), pH 7.2 (2.7mg/ml).

Applications

O-Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

Notes

Store at room temperature. Ensure good ventilation.

Références bibliographiques

D W Gilroy et. Al. Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. Eur. J. Pharmacol. 1998, 355 (2-3),211-217.

K Schrör. Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis. Seminars in Thrombosis and Hemostasis. 1997, 23 (4),349-356.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,851
Beilstein
779271
Code tarifaire harmonisé
2918.22
TSCA
Yes
RTECS
VO0700000

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