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1003-29-8 - Pyrrole-2-carboxaldehyde, 99% - A12838 - Alfa Aesar

A12838 Pyrrole-2-carboxaldehyde, 99%

Numéro CAS
1003-29-8
Synonymes

Dimensions Prix ($) Quantité Disponibilité
10g 51,40
25g 124,00
100g 355,00
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Pyrrole-2-carboxaldehyde, 99%

MDL
MFCD00005217
EINECS
213-705-5

Propriétés chimiques

Formule
C5H5NO
Poids formulaire
95.10
Point de fusion
40-46°
Point d'ébullition
217-219°
Point d'éclair
106°(222°F)
Sensibilité
Air Sensitive
Solubilité
Soluble in chloroform, dimethyl sulfoxide and methanol. Insoluble in water.

Applications

Pyrrole-2-carboxaldehyde is used as a pharmaceutical intermediate. It undergoes condensation reaction to produce pyrrole-2-carboxaldehyde salicylhydrazone (PCSH). It is used as a key starting material for the preparation of pyrrole -2-carboxylic acid by oxidation reaction. It is also used to prepare 4-Difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY dyes) through condensation with a pyrrole, which is an important probes for biotechnology and other applications.

Notes

Store in cool place. Air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong reducing agents and strong bases.

Références bibliographiques

Rawat, P.; Singh, R. N. Eco-friendly synthesis, spectral and computational study of pyrrole-2-carboxaldehyde salicylhydrazone (PCSH) for its application. J. Mol. Struct. 2015, 1100, 105-115.

Otaibi, A. A.; Gordon, C. P.; Gilbert, J.; Sakoff, J. A.; McCluskey, A. The influence of ionic liquids on the Knoevenagel condensation of 1H-pyrrole-2-carbaldehyde with phenyl acetonitriles - cytotoxic 3-substituted-(1H-pyrrol-2-yl)acrylonitriles. RSC Adv. 2015, 4 (38), 19806-19813.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Beilstein
105745
Code tarifaire harmonisé
2933.99
TSCA
Yes

Recommandé

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Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire