Consentement d'utilisation des Cookies

J'accepte. Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

100-66-3 - Anisole, 99% - Methoxybenzene - Methyl phenyl ether - A12997 - Alfa Aesar

A12997 Anisole, 99%

Numéro de CAS
100-66-3
Synonymes
Methoxybenzene
Methyl phenyl ether

Conditionnement Prix ($) Quantité Disponibilité
500g 37,20
2500g 120,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Anisole, 99%

MDL
MFCD00008354
EINECS
202-876-1

Propriétés chimiques

Formule
C7H8O
Poids moleculaire
108.14
Point de fusion
-37°
Point d'ébullition
153-154°
Point d'éclair
43°(109°F)
Densité
0.994
Indice de réfraction
1.5170
Solubilité
Miscible with methanol and acetone. Immiscible with water.

Applications

Anisole is widely used as a solvent for the synthesis of various organic compounds, anethole, nonylphenol isomer 4-(3',6'-dimethyl-3-heptyl)phenol, perfumes, insect pheromones and pharmaceuticals. It finds application in the preparation of inorganic complexes and materials such as tin-core/tin oxide nanoparticles.

Notes

Keep away from sources of ignition. Incompatible with strong oxidizing agents.

Références bibliographiques

The rate of ortho-lithiation of anisole is accelerated dramatically in the presence of TMEDA, effective also in sub-stoichiometric amounts: Tetrahedron Lett., 35, 385 (1994). For discussion of the mechanism of ortho-lithiation, see: J. Org. Chem., 62, 3024 (1997). Although direct dilithiation with n-BuLi/TMEDA was unsuccessful, a sequence involving monolithiation, silylation and further lithiation at the 6-position gave the 2,6-disilyl derivative in 72% yield: J. Org. Chem., 49, 4657 (1984).

Widely used as a carbocation scavenger in the deblocking of, e.g. N-Boc or N-Cbz (Z) peptides with acidic reagents. Addition of anisole removes t-butyl or benzyl cations from the reaction mixture; see, e.g.: J. Chem. Soc., Chem. Commun., 922 (1976); Chem. Pharm. Bull., 25, 2929 (1977); Chem. Ber., 101, 3649 (1968).

Lee, W-S.; Kumar, A.; Wang, Z.; Bhan, A. Chemical Titration and Transient Kinetic Studies of Site Requirements in Mo2C-Catalyzed Vapor Phase Anisole Hydrodeoxygenation. ACS Cata. 2015, 5 (7), 4104-4114.

Peters, J. E.; Carpenter, J. R.; David, D. C. Anisole and Guaiacol Hydrodeoxygenation Reaction Pathways over Selected Catalysts. Energy Fuels 2015, 29 (2), 906-916.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H226-H303-H332-H315-H319-H335

Flammable liquid and vapour. May be harmful if swallowed. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P210-P261-P303+P361+P353-P305+P351+P338-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,669
Beilstein
506892
Classe de danger
3
Groupe d'emballage
III
Code tarifaire harmonisé
2909.30
TSCA
Yes
RTECS
BZ8050000

Recommandé

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire