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148-24-3 - 8-Hydroxyquinoline, 99% - 8-Quinolinol - Oxine - A14720 - Alfa Aesar

A14720 8-Hydroxyquinoline, 99%

Numéro CAS
148-24-3
Synonymes
8-Quinolinol
Oxine

Dimensions Prix ($) Quantité Disponibilité
100g 30,69
500g 93,60
2500g 420,24
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8-Hydroxyquinoline, 99%

MDL
MFCD00006807
EINECS
205-711-1

Propriétés chimiques

Formule
C9H7NO
Poids formulaire
145.16
Point de fusion
72-76°
Point d'ébullition
267°
Sensibilité
Light Sensitive
Solubilité
Almost insoluble in water and diethyl ether. Highly soluble in ethanol, acetone, chloroform, and benzene.Soluble in acetic acid, ethanol, acetone, chloroform, benzene and aqueous mineral acids. Insoluble in water and diethylether.

Applications

8-Hydroxyquinoline is used as an antiseptic and disinfectant. Its alcoholic solution is used in liquid bandages. It is used to prepare tris(8-hydroxyquinolinato)aluminum, which finds application as a component of organic light-emitting diodes (OLED's). It is also used as a reagent and as a stabilizer of hydrogen peroxide in a rocket fuel oxidizer. It is used as a chelating agent and used as a carrier for radio-indium for diagnostic purposes. Its halogenated derivatives are used as anti-infective agents and oral antiamebics.

Notes

Light sensitive. Incompatible with oxidizing agents.

Références bibliographiques

Chelating ligand.

Thinnes, C. C.; Tumber, A.; Yapp, C.; Scozzafava, G.; Yeh, T.; Chan, M. C.; Tran, T. A.; Hsu. K.; Tarhonskaya, H.; Walport, L. J.; Wilkins, S. E.; Martinez, E. D.; Müller, S.; Pugh, C. W.; Ratcliffe, P. J.; Brennan, P. E.; Kawamura, A.; Schofield, C. J. Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases. Chem. Commun. 2015, 51 (84), 15458-15461.

Liang, S. H.; Southon, A. G.; Fraser, B. H.; Krause-Heuer, A. M.; Zhang, B.; Shoup, T. M.; Lewis, R.; Volitakis, I.; Han, Y.; Greguric, I.; Bush, A. I.; Vasdev, N. Novel fluorinated 8-hydroxyquinoline based metal ionophores for exploring the metal hypothesis of Alzheimer’s disease. ACS Med. Chem. Lett. 2015, 6 (9), 1025-1029.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H341-H302

Suspected of causing genetic defects. Harmful if swallowed.

Mentions de prudence: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,4843
Beilstein
114512
Code tarifaire harmonisé
2933.49
TSCA
Yes
RTECS
VC4200000

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