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79-43-6 - Dichloroacetic acid, 99% - A14740 - Alfa Aesar

A14740 Dichloroacetic acid, 99%

Numéro CAS
79-43-6
Synonymes

Dimensions Prix ($) Quantité Disponibilité
100g 22,80
500g 39,20
2500g 123,00
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Dichloroacetic acid, 99%

MDL
MFCD00004223
EINECS
201-207-0

Propriétés chimiques

Formule
Cl2CHCO2H
Poids formulaire
128.94
Point de fusion
9-11°
Point d'ébullition
192-194°
Point d'éclair
>110°(230°F)
Densité
1.564
Indice de réfraction
1.4620
Sensibilité
Hygroscopic
Solubilité
Miscible with water, ethanol, diethyl ether, n-octanol and acetone.

Applications

Dichloroacetic acid salts are used as drugs due to its inhibition of the enzyme pyruvate dehydrogenase kinase. It is also employed to stem the production of lactic acid to treat lactic acidosis. It is clinically essential in children to treat lactic acidosis.

Notes

Incompatible with strong oxidizing agents, strong bases and strong reducing agents.

Références bibliographiques

Moderately strong acid which has been recommended for the catalysis of mixed acetal formation by reaction of alcohols with Ethyl­ vinyl­ ether, A15691 . Has also been used as an acid catalyst and deprotecting agent in various other applications including peptide synthesis.

Ding, Y.; Zhu, J.; Ji, D.; Cao, Y.; Ling, X.; Chen, W. Enhancing adsorption efficiency of dichloroacetic acid onto mesoporous carbons: Procedure optimization, mechanism and characterization. J. Colloid Interface Sci. 2015, 452, 134-140.

Scialdone, O.; Galia, A.; Sabatino, S.; Mira, D.; Amatore, C. Electrochemical Conversion of Dichloroacetic Acid to Chloroacetic Acid in a Microfluidic Stack and in a Series of Microfluidic Reactors. Chem. Electro. Chem. 2015, 2 (5), 684-690.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H314-H351

Causes severe skin burns and eye damage. Suspected of causing cancer.

Mentions de prudence: P260u-P201-P280g-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,3050
Beilstein
1098596
Classe de danger
8
Groupe d'emballage
II
Code tarifaire harmonisé
2915.40
TSCA
Yes
RTECS
AG6125000

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Analytique et matériel de laboratoire