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554-84-7 - 3-Nitrophenol, 98+% - A15312 - Alfa Aesar

A15312 3-Nitrophenol, 98+%

Numéro CAS
554-84-7
Synonymes

Dimensions Prix ($) Quantité Disponibilité
10g 53,90
50g 154,00
250g 634,00
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3-Nitrophenol, 98+%

MDL
MFCD00007240
EINECS
209-073-5

Propriétés chimiques

Formule
C6H5NO3
Poids formulaire
139.11
Point de fusion
93-98°
Point d'ébullition
194°/70mm
Point d'éclair
>100°(212°F)
Densité
1.490
Solubilité
Soluble in water (30 mg/ml), ether, alcohol, acetone, and ethanol (700 mg/ml).

Applications

3-Nitrophenol is used as indicator in 0.3% Soln in 50% alcohol ph: 6.8 Colorless, 8.6 Yellow. It is used in the synthesis of RAGE inhibitors via the etherification of phenols. Also used in the synthesis of kinase inhibitors against epidermal growth factor receptor T790M mutation.

Notes

Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.

Références bibliographiques

A. Alif; P. Boule; J. Lemaire. Photochemistry and environment XII: Phototransformation of 3-nitrophenol in aqueous solution.Journal of Photochemistry and Photobiology A.1990, 50 331-342.

Mohammad R.Haghighi Podeh; Sanjoy K. Bhattacharya; Mingbo Qu. Effects of nitrophenols on acetate utilizing methanogenic systems.Water Research.1995, 29 391-399.

Acid-base indicator: approx pH 6.6 - 8.6.

Has been used for the formation of active esters. These are more stable than the corresponding 4-nitrophenyl esters, but are sufficiently reactive for use in peptide synthesis: Synthesis, 465 (1979).

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H302-H312-H315-H318-H335-H373

Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye damage. May cause respiratory irritation. May cause damage to organs through prolonged or repeated exposure.

Mentions de prudence: P260-P280-P305+P351+P338-P304+P340-P310a-P301+P312a-P321-P405-P403+P233-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF SWALLOWED: Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,6619
Beilstein
1907946
Classe de danger
6.1
Groupe d'emballage
III
Code tarifaire harmonisé
2908.99
TSCA
Yes
RTECS
SM1925000

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Catalyseurs

Analytique et matériel de laboratoire