Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

5470-11-1 - Hydroxylamine hydrochloride, 99% - Hydroxylammonium chloride - A15398 - Alfa Aesar

A15398 Hydroxylamine hydrochloride, 99%

Numéro CAS
Hydroxylammonium chloride

Dimensions Prix ($) Quantité Disponibilité
100g 19,62
250g 26,06
500g 47,28
1000g 70,86
5000g 243,08
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Hydroxylamine hydrochloride, 99%


Propriétés chimiques

Poids formulaire
Point de fusion
152° dec.
Soluble in water, alcohol, methanol and glycerol.


Hydroxylamine hydrochloride is a monomoamine oxidase inhibitor. It is used to prepare oximes and hydroxmic acids in organic synthesis. It acts as a copolymerization inhibitor. It can be used to remove bromine and polybromide from a solution during extraction of lignin from lignocellulosic biomass. It is key starting material for the preparation of pharmaceuticals and agrochemicals. It plays a vital role in rubber and plastic industries as an antioxidant, a vulcanization accelerator and a radical scavenger. It is also used as a color stabilizer and emulsion additive in color films.


Air and moisture sensitive. Incompatible with strong oxidizing agents, phosphorous pentachloride, calcium and anhydrous copper(II) sulfate.

Références bibliographiques

For examples of preparation of oximes from carbonyl compounds, see: Org. Synth. Coll., 2, 70, 313 (1955); 7, 149 (1990). Dehydration of aldoximes is a valuable route to nitriles. The preparation of an oxime, and dehydration with acetic anhydride, are exemplified for veratraldehyde: Org. Synth. Coll., 2, 622 (1943). For other methods of dehydrating oximes to nitriles, see Benzaldoxime, A12053. Procedures for the one-pot conversion of aldehydes to nitriles, without isolation of the intermediate oxime, include: refluxing the aldehyde with hydroxylamine hydrochloride in formic acid/ sodium acetate: J. Chem. Soc., 1564 (1965); formic acid alone: Synthesis, 112 (1979); in pyridine and toluene, with azeotropic water removal: Synthesis, 190 (1982); in DMF (reflux; aromatics only): Z. Chem., 15, 302 (1975); heating in NMP at 110-115o, effective for aromatic and aliphatic substrates; under these conditions, DMF gave only 20-30% conversion: Synthesis, 586 (1999). A more recent ambient temperature one-pot procedure utilizes DBU in combination with ethyl dichlorophosphate: Synlett, 1317 (2007).

For a one-pot synthesis of pyrazoles from aldehydes by cyclization of the intermediate oxime in acidic medium with potassium dihyrogen phosphate, see: Tetrahedron Lett., 47, 43 (2006).

For a brief feature on uses of this reagent in Organic synthesis, see: Synlett, 1326 (2007).

Mahajan, S.; Sharma, B.; Kapoor, K. K. A solvent-free one step conversion of ketones to amides via Beckmann rearrangement catalysed by FeCl 3· 6H 2 O in presence of hydroxylamine hydrochloride. Tetrahedron Lett. 2015, 56 (14), 1915-1918.

Wang, W.; Zhao, X. M.; Wang, J. L.; Geng, X.; Gong, J. F.; Hao, X. Q.; Song, M. P. Transition metal-free synthesis of primary amides from aldehydes and hydroxylamine hydrochloride. Tetrahedron Lett. 2014, 55 (20), 3192-3194.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H351-H373-H290-H315-H319-H400-H302-H312-H317

Suspected of causing cancer. May cause damage to organs through prolonged or repeated exposure. May be corrosive to metals. Causes skin irritation. Causes serious eye irritation. Very toxic to aquatic life. Harmful if swallowed. Harmful in contact with skin. May cause an allergic skin reaction.

Mentions de prudence: P273-P280h-P406

Avoid release to the environment. Wear protective gloves/clothing. Store in corrosive resistant container with a resistant inner liner.

Autres références

Classe de danger
Groupe d'emballage
Code tarifaire harmonisé


  • A12005

    Pyridine, 99+%
  • A15364

    4-Methoxybenzaldehyde, 98%
  • 36439

    Trisodium citrate dihydrate, ACS, 99.0% min
  • 36602

    Zinc granules, ACS, -20 mesh, 99.8% min
  • 40476

    Bismuth hydroxide nitrate oxide, Bi<sub>2</sub>O<sub>3</sub> 79% min

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux


Analytique et matériel de laboratoire